by Nagoya University – Technology Networks –

A human stem cell-derived pituitary tissue transplant restored hormone signaling in a primate with hypopituitarism.

Researchers in Japan have transplanted pituitary tissue grown from human stem cells into a primate whose pituitary gland had been surgically removed, successfully restoring critical hormone signals. Led by researchers from Nagoya University in Japan, the team showed that the same method worked in mice over a longer period. This is the first time lab-grown human pituitary cells have been shown to work and survive after transplantation into a primate. The study, published in the journal Stem Cell Research & Therapy, may offer a new pathway for treating lifelong hormone disorders.

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