News and Opinions
After allogeneic transplant, VIC-1911 regimen shows low severe GVHD and no relapse
by Roswell Park Comprehensive Cancer Center - MedicalXPress - Results of a Phase I clinical trial show that patients who undergo a blood stem cell transplant involving a donor have a lower risk of relapse and lower rates of graft-versus-host disease when they receive...
Nobel Prize winners face new loss in bid for US CRISPR patents
By Blake Brittain - Reuters News - March 27 (Reuters) - A U.S. Patent Office tribunal has ruled against Nobel Prize-winning scientists Jennifer Doudna and Emmanuelle Charpentier for a second time in their dispute with the Broad Institute, a joint venture of Harvard...
U.S. judge upends Kennedy’s overhaul of childhood vaccine policies
By CNBC NEWS - A federal judge on Monday blocked key parts of Health Secretary Robert F. Kennedy Jr.’s effort to reshape U.S. vaccine policy, including a move to reduce the number of shots routinely recommended for children. U.S. District Judge Brian Murphy in Boston...
Cells can sense 10x farther than expected and it may explain cancer spread
By Washington University in St. Louis - Science Daily - Scientists have discovered that cells can sense far beyond the surfaces they touch. While individual cancer cells can probe about 10 microns ahead by tugging on surrounding collagen fibers, clusters of normal...
New RNA injection could help hearts heal after heart attacks
By Drug Target Review - A new RNA-based therapy developed at Columbia University could help the heart repair itself after a heart attack without invasive surgery. After a heart attack, it is possible for cardiologists to reopen blocked vessels and restart blood flow...
Japan Approves the World’s First Treatment Made With Reprogrammed Human Cells
By Ritsuko Kawa - Wired - Researchers in Japan pioneered reprogrammed cells 20 years ago. Now the country has given the first-ever authorizations to manufacture and sell medical products based on the technology. On March 6, Japan’s Ministry of Health, Labor and...
With FDA go ahead, a China biotech notches a first in cell therapy testing
by Jacob Bell - BioPharmaDive - The agency has now cleared Shanghai-based Unixell to begin human studies in the U.S. for an allogeneic, stem cell-derived therapy targeting focal epilepsy. For the first time, the Food and Drug Administration is allowing a certain kind...
FDA must regulate stem cell therapies to mitigate risks to patients and the public
By PNAS.org - In December 2025, the US Food and Drug Administration’s (FDA’s) Center for Biologics Evaluation and Review (CBER) approved a gene-based stem cell therapy for Wiskott–Aldrich syndrome, a rare and life-threatening genetic disease. This decision was...
Gene-based therapies poised for major upgrade thanks to Oregon State University research
By Steve Lundeberg - Oregon State University - by overcoming the challenge of consistently getting genes and gene-editing tools where they need to be within cells. Findings of the study spearheaded by Oregon State University College of Pharmacy graduate student Antony...
Giving stem cells room to breath
By Kyoto University - Nanogel integrated spheroids increase cell retention and repair injured swallowing muscles Kyoto, Japan -- Swallowing is a fundamental human function that supports nutrition and communication. Damage to swallowing muscles can reduce quality of...
New hope for treating a rare genetic disease before birth
By Stanford Medicine News - Stanford Medicine scientists are launching a clinical trial of prenatal transplants, using stem cells from the mother, to treat a rare genetic disease called Fanconi anemia before a baby is born. Stanford Medicine pediatric hematologist...
Scientists Are Trying to Train Lab-Grown Brains. The Brains Have Started to Solve Problems.
By Darren Orf - Popular Mechanics - Scientists trained a brain organoid to solve a well-known engineering task, and its success demonstrates the increasing complexity of lab-grown brains. While creating organs sounds like sci-fi fodder, scientists have actually...
Henrietta Lacks’ Family Gets Undisclosed Settlement In “Immortal Cells” Case
by James Felton - IFLScience - Swiss pharmaceutical company Novartis has settled a lawsuit by the estate of Henrietta Lacks, which alleged that the company unfairly profited from her "immortal" cell line, taken without her knowledge or consent in 1951 and still widely...
The Gene Fixer – For five decades, Stuart Orkin has harnessed new genetic tools
By Elizabeth Dougherty - Dana-Farber Cancer Institute - In the early 1970s, the field of genetics was confined to the study of bacteria and viruses. Conventional wisdom at the time was that the tools of molecular biology couldn't be used to study human diseases. Human...
Teenage daughter’s bone marrow saves dad’s life
By Erin Baily - UC Davis Health - For Hai Trinh, his disease started gradually. Fatigue. Bruising easily. He thought little of it. As a mechanic, husband and father of two girls, he just kept pushing forward, attributing the persistent health challenges to his long...
Woman shares leukemia battle, partial-match stem cell treatment with 1.5 million on social media
By Jamie Bartosch - UChicago Medicine - “I was so sick and tired; I knew I couldn’t keep doing chemo,” said Cordle, 51, who lives in Mapleton, Illinois, just outside Peoria. The next step would be stem cell transplantation, also known as bone marrow transplantation....
CAR T-cell Therapy Improves Survival in Relapsed or Refractory Lymphoma
By Melissa Rohman - NorthWwestern Medicine - CAR T-cell immunotherapy improved progression-free and overall survival in patients with relapsed or refractory marginal zone lymphoma, according to a recent clinical trial published in The Lancet. Marginal zone lymphoma...
New iron nanomaterial wipes out cancer cells without harming healthy tissue
By Oregon State University - Science Daily - Scientists at Oregon State University have engineered a powerful new nanomaterial that zeroes in on cancer cells and destroys them from the inside out. Designed to exploit cancer’s unique chemistry—its acidity and high...
More Sensitive Cell Therapy May Be a HIT Against Solid Cancers
By Columbia University Irving Medical Center - CAR-T cell therapy has revolutionized the treatment of many blood cancers, but has shown little success against solid tumors, which account for over 85% of all cancers. Columbia researchers have now found that a new type...
Seattle jury awards $24M in lawsuit against stem cell center
By Elise Takahama - Seattle Times - A King County jury has awarded $24 million to the family of a man who died a day after treatment at a Seattle stem cell center. Mike Trujillo was 62, a longtime electrician who ran an electrical company in Colorado. After being...
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