by Tokyo Metropolitan University – MedicalXpress –
Researchers from Tokyo Metropolitan University have developed a way to treat age-related muscular atrophy using regenerative medicine. Conventional methods to implant myoblasts, precursors to muscle fiber, require prior scarring for the new cells to graft properly. By adding extracellular matrix (ECM) fluid into the implant, the team successfully grafted myoblasts onto healthy muscle in mice. Their technique opens the way for using implantation to treat unscarred muscle atrophied by aging.
The work is published in the journal Frontiers in Cell and Developmental Biology.