News and Opinions

by Laura Kelley - University of Colorado Cancer Center - Researchers at CU Anschutz Medical Campus have developed ALA-CART, a next-generation therapy aimed at improving outcomes for patients with resistant cancers. “This next-generation approach, called ALA-CART...

by Morgridge Institute for Research - MedicalXpress - Scientists at the Wisconsin National Primate Research Center (WNPRC) and the Morgridge Institute for Research at the University of Wisconsin–Madison have been at the forefront of stem cell research and regenerative...

By Frank Vinluan - MedCity News - Neurotech Pharmaceuticals’ surgically implanted cell and gene therapy, Encelto, is now FDA approved to treat macular telangectasia type 2 (MacTel). It’s the first therapy for this rare retinal degeneration disorder. Protein therapies...

By Mass General Brigham - A recently launched Phase 1 clinical trial at Mass General Brigham is examining the safety and feasibility of a groundbreaking treatment approach for Parkinson’s disease in which a patient’s stem cells are reprogrammed to replace dopamine...

By Technology Networks - Reprogrammed stem cells to replace dopamine cells in the brain may offer hope for Parkinson's treatment. A recently launched Phase 1 clinical trial at Mass General Brigham is examining the safety and feasibility of a groundbreaking treatment...

By Mass General Brigham - An expanded clinical trial that tested a groundbreaking, experimental stem cell treatment for blinding cornea injuries found the treatment was feasible and safe in 14 patients who were treated and followed for 18 months, and there was a high...

By Technology Networks - A new, alternative treatment for wet AMD involves the transplantation of stem cell-derived retinal cells. Age-related macular (AMD) degeneration is a leading cause of vision impairment and blindness in the elderly population. In so-called wet...

By Pharmaceutical Technology - AI can enhance the drug discovery process of regenerative medicine by tackling the primary challenges associated with the process. As the field of regenerative medicine continues to advance, the incorporation of AI is playing a...

By Technology Networks - New research has found hematopoietic stem cells in human lung tissue that make red blood cells. Red blood cells carry oxygen from the lungs to every other organ, and blood-forming stem cells must make about 200 billion new red blood cells each...

By Tulane University - MedicalXpress - Tulane University researchers have developed a CRISPR-based test that diagnoses Pneumocystis jirovecii pneumonia (PJP)—a life-threatening fungal infection primarily affecting children and immunocompromised patients—more quickly...

By UCLA News - UCLA researchers are developing a gene-editing platform that aims to correct the root cause of the disease Imagine a future where treating cystic fibrosis is as simple as taking a deep breath. That’s exactly what a team of pediatric physician-scientists...

BY JAKE REDER, CEO OF CELDARA MEDICAL - INC - Though most biopharma investment is in two states, follow this model to bring the research—and investments—elsewhere. The majority of Americans do not live in a biotech hub. Yet 62 percent of all U.S. biopharma venture...

By Drug Target Review - CAR-T therapy has shown effectiveness in cancer treatment, but relapse often occurs due to limited cell persistence. New strategies aim to improve CAR T-cell durability for longer lasting remission. immunotherapy has emerged as one of the most...

By UVA Health - A surprising discovery from the School of Medicine is transforming our understanding of hair growth and could set the stage for new approaches to cure hair loss. Researchers led by UVA’s Lu Q. Le, MD, PhD, have discovered that a previously...

By News Medical Life Sciences - The immune system’s natural killer (NK) cells are large granular cells that constitute the third major lymphocyte subset, representing around 10-15% of circulating lymphocytes in the blood. Natural killer cells are a vital part of the...

By UCI Health News - The California Institute for Regenerative Medicine (CIRM) has awarded a UC Irvine neuroscientist $4.6 million to advance studies of a novel immunotherapy that holds the potential to revolutionize cancer treatment by targeting all major cancer...

By Drug Target Review - Regenerative medicine is set to be transformed by induced pluripotent stem cells (iPSCs). These versatile cells can be reprogrammed to become virtually any cell type in the human body, offering groundbreaking possibilities for treating a wide...

by The Scientist - Stem cells form the backbone of many cell-based therapies due to their unique properties, including the ability to self-renew and differentiate to many cell types. Multiple cell therapies deliver exogenous bone marrow stem cells into patients, which...

By Jacob Smith - Nature - CAR T remission breaks record - A woman who received CAR-T-cell therapy to treat a nerve-cell cancer when she was 4 years old is still cancer-free 19 years later, the longest reported cancer remission following the treatment. She received the...

by Tokyo Metropolitan University - MedicalXpress - Researchers from Tokyo Metropolitan University have developed a way to treat age-related muscular atrophy using regenerative medicine. Conventional methods to implant myoblasts, precursors to muscle fiber, require...