News and Opinions
Engineered Bone Marrow Model Advances CRISPR-CAR T Research in AML
By Genetic Engineering and Biotechnology News - Scientists at the University of Glasgow developed a bioengineered bone marrow (BM) model that helped them to evaluate potential use of a combined CRISPR-CAR T cell therapy in the treatment of acute myeloid leukemia. The...
Scientists discover how hair cells can help heal skin faster
By Rockefeller University - ScienceDaily Scientists found that low serine levels spark a shift in hair stem cells, transforming them into wound-healing experts — with diet playing a possible role. Rockefeller scientists uncovered how hair follicle stem cells can...
Behind the FDA’s Elimination of REMS Program for CAR T-Cell Therapies
By Jonah Feldman, Frederick Locke, MD - Targeted Oncology - On June 26, 2025, the FDA announced the elimination of the Risk Evaluation and Mitigation Strategy (REMS) program that applied to 6 chimeric antigen receptor (CAR) T-cell therapies approved to treat patients...
What will be born of the marriage of de-extinction firm Colossal and animal cloning biotech Viagen?
By Paul Knoepfler - STAT - The company that claimed to revive the dire wolf continues to raise ethical questions De-extinction firm Colossal Biosciences announced Tuesday that it was acquiring animal cloning firm Viagen. The same day, retired NFL all-star Tom Brady...
SwRI-developed single-use 3D-printed bioreactor harvests induced Pluripotent Stem Cells
By Medical Life Sciences News - Southwest Research Institute (SwRI) has demonstrated a new application for its cell-expansion bioreactor to advance tissue engineering and cell-based therapies for treatment of injuries and diseases. SwRI scientists used the bioreactor...
Technical University of Munich transforms stem cells into bone cells
By Optics.org - A project at the Technical University of Munich (TUM) has successfully stimulated stem cells in a manner that reliably induced them to develop into bone cells. The technology could ultimately lead to ways to generate specific cells for biomedical...
Japanese Researchers Develop Method to Repair Spinal Fractures Using Fat-Derived Stem Cells
by GOAI -Gene Online - Japanese researchers are exploring a novel, minimally invasive method to repair spinal fractures using body fat-derived cells. The experimental approach involves converting fat cells into bone tissue, offering a potential alternative to...
Scientists see foam as starting point of a path to bedside gene therapy
By Sabrina Richards - Fred Hutch Cancer Center - Bioengineer Dr. Matthias Stephan developed a quick-foaming solution that he hopes could one day turn gene therapy into an outpatient procedure The special properties of methylcellulose foam could make it a vehicle for...
Dementia researchers cheer Texas voters’ approval of $3 billion funding initiative
By Jennie Erin Smith - Science - New effort is modeled after the state’s long-running cancer research institute Texas voters this week made a bet that their state could build on a legacy of success in cancer research and become a powerhouse in neurological research as...
Salamanders can regrow limbs. Could humans someday?
by Kermit Pattison – Harvard Gazette – Findings on adrenaline’s role in process raise new possibilities for regenerative medicine Biologists long have been fascinated by the ability of salamanders to regrow entire limbs. Now Harvard researchers have solved part of...
Stanford makes stem cell transplants safer without chemo
By Stanford Medicine - ScienceDaiiy - A Stanford-led team has replaced toxic pre-transplant chemotherapy with a targeted antibody, allowing children with Fanconi anemia to receive stem cell transplants safely. The antibody, briquilimab, removes diseased stem cells...
Anti-fibrotic effect of human amniotic fluid stem cells in biliary epithelial-mesenchymal transition of liver ductal organoid
By Stem Cells Translational Medicine - Abstract Purpose In biliary atresia (BA), it has been demonstrated that biliary epithelial-mesenchymal transition (EMT) of reactive ductular cells is associated with liver fibrosis. This study aimed to develop an ex vivo biliary...
Lab-grown liver model offers a platform to study fibrosis and regeneration
by Institute of Science Tokyo - MedicalXpress - As chronic liver disease becomes more widespread, researchers at Science Tokyo have developed a lab-grown organoid that replicates a regenerating liver, offering new hope for future treatments. The model recreates...
How A New AI Model Exposes A Hidden Weakness In Cancer Cells
By William A. Haseltine - Forbes - New research from DeepMind and Yale University has created AI that now generates biological hypotheses that can lead to new medical discoveries. The collaboration between recently produced C2S-Scale 27B, a powerful AI model trained...
Scientists 3D print muscle tissue in zero gravity to study diseases beyond Earth
By Aamir Khollam - Interesting Engineering - In a leap that could reshape how scientists study the human body in space, researchers at ETH Zurich have successfully 3D printed muscle tissue in conditions mimicking weightlessness. The achievement brings scientists...
Stroke Damage Reversed As Stem Cells Regrow the Brain
By University of Zurich - SciTechDaily - Stem cell therapy reversed stroke damage in mice, regenerating neurons and restoring movement. The findings bring scientists closer to human treatments that could one day transform recovery after brain injury. Breakthrough in...
Microencapsulated 3D culture of human umbilical cord-derived mesenchymal stem cells enhances their therapeutic effect on intrauterine adhesion Open Access
By Stem Cells Translational Medicine - Abstract Therapeutic application of mesenchymal stem cells is emerging as a potential strategy for the management of intrauterine adhesion (IUA). However, conventional 2D cultures often face issues such as insufficient cell...
‘My hero’: 9-year-old boy helps father fight cancer with stem cell donation
By KCAL/KCBS via CNN Newsource Watch Video - A 9-year-old California boy is being called a hero after he saved his father’s life with a stem cell donation. Nick Mondek, a 45-year-old father of two, was facing a second battle with leukemia in April when his...
CAR NK cell therapy clinical trial puts follicular lymphoma survivor into remission
By Cynthia DeMarco - MD Anderson Cancer Center - When JC Cox was diagnosed with a type of non-Hodgkin lymphoma called follicular lymphoma in 2006, the now-retired HVAC technician sought treatment close to his home in Dallas. But several rounds of strong chemotherapy...
Stem cell therapy linked to lower risk of heart failure after a heart attack
By BMJGroup - Technique may be a valuable add-on procedure for patients with weak heart function after a heart attack, say researchers Patients with weak heart function who receive stem cell therapy shortly after a heart attack are at lower risk of developing heart...
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