News and Opinions
Brain tumor organoids accurately model patient response to CAR T cell therapy
by Penn Medicine News - Lab-grown tumors respond to cell therapy the same as tumors in the patients’ brains, according to Penn researchers PHILADELPHIA— For the first time, researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM)...
Unlocking the secrets of collagen: How sea creature superpowers are inspiring smart biomaterials for human health
by University of North Carolina at Charlotte - Phys.org - Major findings on the inner workings of a brittle star's ability to reversibly control the pliability of its tissues will help researchers solve the puzzle of mutable collagenous tissue (MCT) and potentially...
Australia’s Fast New 3D Bioprinter Can Mimic Human Tissues
By Karoline Kan - Bloomberg - Have you ever imagined seeing human tissues and organs created by lab machines, within seconds? That may soon become reality — and not just a scene from science fiction. Read on... Click here to read the full article
UNL researchers delving into which foods help slow aging of brain
By Aaron Sanderford - Eastern Progress - LINCOLN — Beef may not only be “what’s for dinner,” but may help slow the aging of our brains. That’s what researchers at the Center for Brain, Biology and Behavior at the University of Nebraska-Lincoln seek in what’s described...
8 Trends to Watch in the Cell and Gene Therapy Market
By Karen Blum - Specialty Pharmacy Continuum - An increase in rare/ultra-orphan treatments, along with a boom in cell and gene therapies and ambulatory infusion centers, are among developments to prepare for in the increasingly competitive specialty pharmacy market....
A pilot raced through the airport to surprise an old friend: the woman who saved his life
By Dalia Faheid and Maria Sole Campinoti - CNN News - When Allie Reimold boarded Flight 2223 in Houston a week ago, she didn’t expect to see him. It had been four years since they’d last visited in person. And eight years, almost exactly, since the budding scientist –...
Xenogeneic-free culture of human intestinal stem cells for scalable, clinical-grade stem cell therapy
By <a href="https://www.nature.com/articles/s41467-024-54653-9">Nature Communications</a> - The need for basement membrane extract (BME) with undefined constituents, such as Matrigel, for intestinal stem cell (ISC) culture in traditional systems poses a...
New Gene Therapy Reverses Heart Failure in Large Animal Model
By University of Utah Health - A new gene therapy can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the heart can pump and dramatically improves survival, in what a paper describing...
Using cellular therapy to treat cancer, and beyond
By Scott Reading - University of Michigan Medicine - A cell therapy clinician talks about the treatment and its promising future to treat other diseases, too Advancements in using a person’s own cells to treat disease have been growing for years. These include...
Tiny sensors offer new hope for faster bone injury recovery
by Rachel Lukowicz-Bedford, University of Oregon - MedicalXpress - Tiny implantable sensors are helping University of Oregon researchers optimize the process of recovery from severe bone injuries. Scientists at the UO's Phil and Penny Knight Campus for Accelerating...
The global divide between longer life and good health
By Susan Buckles - Mayo Clinic - Rochester, Minn. — People around the globe are living longer — but not necessarily healthier — lives, according to Mayo Clinic research. A study of 183 World Health Organization (WHO) member countries found those additional years of...
Scientists Decipher How Marine Worms Regrow Lost Body Parts
by Technology Networks - Marine worms regenerate lost body parts by dedifferentiating cells, offering insights into natural cell reprogramming. Researchers at the Max Perutz Labs have uncovered how marine worms regenerate lost body segments. The study reveals that...
Keto diet metabolite may power up CAR T cells to kill cancer
By Penn Today - Laboratory studies reveal a potentially low-tech intervention to improve personalized cell therapy. A simple dietary supplement may provide a new approach to boost CAR T cell function, according to a study from researchers in Penn’s Perelman School of...
New drug tested to reduce side effect of ‘half-matched’ stem cell transplants
by Julia Evangelou Strait - WashU Medicine - Clinical trial indicates safety, fewer cases of life-threatening graft-versus-host disease than expected Adding a new drug to standard care for stem cell transplant recipients may reduce a life-threatening side effect,...
Newly discovered mechanism in the cell’s energy factory can lead to new treatment of muscle disorders
By University of Copenhagen - Researchers have discovered a mechanism in our cells that is essential to energy production in the muscles. The discovery may lead to new treatment for disorders affecting the muscles, like diabetes, cancer and cardiovascular disease....
Socioeconomic Barriers Limit Access to Lifesaving Stem Cell Transplants in AML
By Silas Inman - Cancer Network News - The ability to undergo an allogeneic hematopoietic stem cell transplant (allo-HCT), the only potentially curative therapy for patients with acute myeloid leukemia (AML), is significantly influenced by socioeconomic factors with...
Ketogenic Diet Enhances CAR-T Cancer Therapy
By Neuroscience News - Researchers have found that a ketogenic diet boosts CAR T cell therapy effectiveness by enhancing tumor control and survival in mice with lymphoma. The key is beta-hydroxybutyrate (BHB), a metabolite produced during ketosis, which CAR T cells...
Is exosome therapy the future of hair loss treatment? Expert insights
by Dr Rinky Kapoor - Healthcare Radius - Exosomes, which are nanoscale extracellular vesicles derived from mesenchymal stem cells (MSCs), encapsulate a diverse array of bioactive molecules, including proteins, lipids, and nucleic acids, that facilitate intercellular...
How FIRM is Shaping Regenerative Medicine in Japan
by Bernice Lottering - Gene Online - Regenerative medicine, as a whole, is in a critical position to transform healthcare and confront several critical challenges that threaten its widespread adoption. High costs, complex development processes, and intricate...
High-fiber diet cuts risk of rejected bone marrow and stem cell transplants, cancer research discovers
By Benjamin Ferrer - Nutrition Insight - Scientists and physicians with the US-based cancer research and treatment organization City of Hope are presenting new research on high-fiber dietary interventions for bone marrow and stem cell transplant patients at risk for...
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