News and Opinions
Stem cell transplant transforms life of toddler with beta thalassemia major
By Lynn Nicho;ls - Stanford Medicine - From Frequent Transfusions to a Cure for Beta Thalassemia Wade Huynh, age 3, was born with a serious blood disorder, and he needed a stem cell transplant to thrive. Luckily, he didn’t need to look far for a donor match—just...
One step closer to 3D printing inside the body
By Healthcare-in-Europe.com What if doctors could precisely print miniature capsules capable of delivering cells needed for tissue repair exactly where they are needed inside a beating heart? A team of scientists led by Caltech has taken a significant step toward that...
Gene-edited stem cells aim to reverse rheumatoid arthritis
by Max G. Levy, PhD - Drug Discovery News - At the root of anything good or bad in the human immune system is a question about recognition. When the immune system functions correctly, it clocks unrecognized bacteria and viruses. When it misbehaves, immune cells...
Cracking the code to scalable cell and gene therapy
by Drug Target Review - Cell and gene therapy (CGT) is advancing rapidly, offering new treatments for complex conditions such as cancer and genetic disorders. As these therapies evolve, the demand for more efficient and reliable methods of cell expansion – an...
New Cell Therapy For Resistant Hodgkins Patients
By Derek Lowe - Science - Here’s some more good news on the immuno-oncology front. Hodgkin lymphoma (HL) is one of those cancer types whose prognosis is in the “A lot better than it used to be, but. . .” category. There are several varieties (with the “classic” form...
The stem cell race for Parkinson’s disease: Recent studies show significant promise
By Willow Shah-Neville - LabBioTech - Parkinson’s disease is an extremely complex condition to treat. Although there are medications available that can help relieve symptoms, there are still no approved therapies that slow down the progression of the underlying...
Federal appeals court sends CRISPR-Cas9 patent case back to patent office for reconsideration
By Robert Sanders - UC Berkley News - In a decision released today (May 12), the U. S. Court of Appeals for the Federal Circuit in Washington, D.C., ordered the U.S. Patent and Trademark Office’s Patent Trial and Appeal Board (PTAB) to reconsider its 2022 interference...
Embryonic macrophages found to control blood stem cell numbers in bone marrow
by Kerstin Wagner, Leibniz - MedicalXpress.com - Scientists at the Leibniz Institute on Aging—Fritz Lipmann Institute (FLI) in Jena have discovered a previously unknown function of immune cells in the bone marrow. Embryonic macrophages—specialized phagocytes of the...
Biotech Tango dances away from preclinical work to extend cash runway, while Avalo lays out spending options
By Nick Paul Taylor - Fierce Biotech - Biotech bank balances were again in focus Monday morning, with Tango Therapeutics cutting preclinical work to stretch its cash runway and Avalo Therapeutics outlining options for preserving its money. Tango extended its cash...
Infant becomes world’s first patient to undergo personalized gene-editing treatment
By Jon LaPook - CBS NEWS - Philadelphia — Soon after KJ Muldoon was born in the summer of 2024, he was diagnosed with a rare genetic disorder that is fatal for about half the infants who are born with it. Until now, the only effective long-term treatment for the rare...
Stem cell model replicates human amniotic sac development past two weeks
by The Francis Crick Institute - Phys.Org - Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four weeks after fertilization....
CAR T-Cell Therapy: New Advances Move On Past Setbacks
By Tiffany Yesavag - Genetic Bioengineering & Biotechnology News - Chimeric antigen receptor (CAR) T-cell therapy is an innovative cancer treatment that engineers a patient’s own T cells to target and destroy cancer cells. While the field has sparked significant...
Natural molecule reverses age- and dementia-related cognitive decline
By Paul McClure - News Atlas - In a new study, researchers identified a molecule produced by a particular type of brain cell that reversed the cognitive decline seen in both healthy aging and dementia. It provides a deeper understanding of the aging process and a...
Aging Decoded: Terms You Need to Know – Healthspan Compass Podcast Episode 2
By Kevin McMahon - Healthspan Action Coalition - Join our hosts, Junaid Mian of 1435 Capital Management and Melissa King from the Healthspan Action Coalition for this edition of Healthspan Compass. In this episode, our hosts aim to establish a foundational...
Gene Therapy Restores Immune Function in Children With Rare Disorder
by University of California Los Angeles - Technology Networks - An investigational gene therapy has successfully restored immune function in all nine children treated with the rare and life-threatening immune disorder called severe leukocyte adhesion deficiency-I, or...
Inaugural graduates in Translational Biotechnology Master of Science prepared for impactful careers in STEM
Press Release by Atrium Health Wake Forest Baptist - May 15, 2025 - Dr. Minni Saluja enrolled in the Translational Biotechnology Master of Science program at the Wake Forest Institute for Regenerative Medicine because she was interested in the role regenerative...
New MRI technique lights up ‘zombie cells’ that contribute to arthritis
By Rachel Tompa - Stanford Medicine - Research led by Stanford Medicine points to the first non-invasive imaging method to visualize senescent cells, which are alive but dormant and play a key role in many diseases. Anyone who’s had a knee or other joint replacement...
The best and brightest young scientists are looking beyond the U.S. as cuts hit home
By Evan Bush - NBS News - Jack Castelli had it all figured out. The University of Washington doctoral student had spent the past three years developing new gene-editing techniques that could spur immunity to the virus that causes AIDS. Early testing in mice showed...
Enhanced CAR T cell therapy offers new strategy for lymphoma
By Meagan Raeke - Penn Medicine News - PHILADELPHIA – A next-generation “armored” CAR T cell therapy showed promising results in a small study of patients whose B-cell lymphomas continued to resist multiple rounds of other cancer treatments, including commercially...
Bioprinted Aorta Shows Promise for Cardiovascular Disease Treatment
by Isabella Backman - Yale School of Medicine - Yale researchers have built a 3D-bioprinted synthetic aorta that they have successfully implanted into rats. This technology could advance the treatment of cardiovascular diseases such as coronary artery disease or...
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