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High-throughput 3D engineered paediatric tumour models for precision medicine

High-throughput 3D engineered paediatric tumour models for precision medicine

by admin | Oct 22, 2025 | News & Opinions

By Molecular Systems Biology – Abstract Precision medicine for paediatric and adult cancers that incorporates drug sensitivity profiling can identify effective therapies for individual patients. However, obtaining adequate biopsy samples for high-throughput...
New CAR T therapy targets solid tumours safely and effectively

New CAR T therapy targets solid tumours safely and effectively

by admin | Oct 21, 2025 | News & Opinions

By Drug Target Review – USC researchers have engineered CAR T cells to deliver a dual protein therapy that targets solid tumours – offering hope for cancers previously resistant to treatment. Chimeric antigen receptor (CAR) T-cell therapy, which uses a patient’s...
Takeda Exits Cell Therapy Amid Strategic Pivot, Dealing Blow to Once Promising Modality

Takeda Exits Cell Therapy Amid Strategic Pivot, Dealing Blow to Once Promising Modality

by admin | Oct 20, 2025 | News & Opinions

by Tristan Manalac – BioSpace – Takeda is looking to offload its cell therapy platform and preclinical assets to a yet-unidentified external partner. 137 employees will be let go as part of the move. Takeda will no longer invest in cell therapies moving...
New Tool Identifies Proteins That Control Gene Activity

New Tool Identifies Proteins That Control Gene Activity

by admin | Oct 17, 2025 | News & Opinions

by Weill Cornell Medicine – he SCOPE system can capture proteins binding to regions of DNA that control gene expression. The illustration depicts part of the process where a small guide RNA delivers a protein bearing a special amino acid to the desired region....
This “chaos enzyme” may hold the key to stopping cancer spread

This “chaos enzyme” may hold the key to stopping cancer spread

by admin | Oct 16, 2025 | News & Opinions

By Science Daily – A Weill Cornell Medicine team has found that triple-negative breast cancer depends on the enzyme EZH2 to spread. By silencing key genes, EZH2 drives chaotic cell divisions and fuels metastasis. Blocking EZH2 restored stability and prevented...
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