Engineered stem cells target autoimmune diseases

Engineered stem cells target autoimmune diseases

By Adam Boros, PhD – Drug Discovery News – Genetically modified stem cells show promise in a targeted approach to taming inflammation in autoimmune diseases. Researchers developed an immunotherapy using chimeric antigen receptors and mesenchymal stromal...
Prime Editing Corrects Cystic Fibrosis Mutation

Prime Editing Corrects Cystic Fibrosis Mutation

by Gorm Pamgren – CRISPR Medicine News – Researchers have refined prime editing (PE) to correct the cystic fibrosis (CF) related gene CFTR. Results demonstrated improved efficiency and minimal off-target effects in correcting the F508del mutation in human...