News and Opinions

By Carolyn Y. Johnson - The Washington Post - For years, Amanda Smith and her husband were jolted awake at night by a buzz-buzz-beep — an alarm warning that her blood sugar was too high or too low. She would reach for juice boxes stored in her nightstand or fiddle...

By Mary Ann Liebert, Inc Publishers - This cover illustrates the original research report submitted by Anastasia Khvorova of the RNA Therapeutics Institute, University of Massachusetts Chan Medical School. This gorgeous image depicts the observation that nuclear...

By Sara Youngblood Gregory  - Mayo Clinic - For many scientists and doctors, immunotherapy that uses someone’s own immune system to target and attack cancer cells is the next and best frontier of cancer treatment. Over the last decade, immunotherapy-focused research...

By Fay Ghani, Abba C. Zubair - Nature - Stem cell research performed in space has provided fundamental insights into stem cell properties and behavior in microgravity including cell proliferation, differentiation, and regeneration capabilities. However, there is...

by Julia Evangelou Strait - Washington University College of Medicine - Detailed blueprint of nerve cells’ dramatic changes could help identify ways to heal spinal cord damage. Zebrafish are members of a rarefied group of vertebrates capable of fully healing a severed...

By University of Cambridge - Researchers have discovered a way to extend the shelf life of blood stem cells outside the body for use in gene therapy, providing patients with better options and improving their outcomes. We were able to identify a key molecular...

By The National Cancer Institute - In November 2023, the Food and Drug Administration announced that it was investigating more than 20 instances of second cancers—specifically, T-cell lymphomas—in people who had been treated with CAR T-cell therapies. In several...

By Technology Networks - Research offers new hope for treating neurodevelopmental disorders by activating dormant neural stem cells. Scientists from Duke-NUS Medical School and the Mechanobiology Institute (MBI) at the National University of Singapore (NUS) have...

By University of Louisville School of Medicine - A new stem cell therapy for heart failure is being tested in patients at the University of Louisville and UofL Health. The trial is the first in the U.S. to test umbilical cord-derived stem cells in patients for heart...

By University of Louisville School of Medicine - A new stem cell therapy for heart failure is being tested in patients at the University of Louisville and UofL Health. The trial is the first in the U.S. to test umbilical cord-derived stem cells in patients for heart...

By Natalie Healey - Nature Medicine Going from the laboratory to an approved therapy in 11 years is no mean feat. That is the story of the world’s first approved CRISPR–Cas9 therapy, greenlit by the US Food and Drug Administration in December 2023....

By Inside Precision Medicine - The immunotherapy afamitresgene autoleucel (afami-cel) for the treatment of adults with the rare soft tissue cancer called synovial sarcoma was granted accelerated approval late last week by the U.S. Food and Drug Administration (FDA)....

By University of Barcelona - A study published in The EMBO Journal opens new perspectives to better understand how the molecular mechanisms involved in regenerative medicine work. The study focuses on tumour necrosis factor-α (TNF-α) and its receptors TNFR, molecules...

by Molly Coddington - Technology Networks - Like many young girls in elementary school, Victoria Gray wanted to be a cheerleader, until she was told by her doctor that this simply wouldn’t be possible; the exertion placed on her body by the training regimen could have...

by Marla Broadfoot, Ph.D. - Mayo Clinic - Pancreatic cancer is a formidable disease, often diagnosed too late for effective treatment. However, new research from Mayo Clinic represents a promising step toward identifying biological signals or biomarkers that may aid...

By Priya Baraniak - STAT News - Cutting-edge FDA-approved therapies made from human cells are now being used to treat cancer, diabetes, and other diseases. Currently, most approved cell-based therapies use an individual’s own cells, but the next generation of these...

By Medical Xpress News - In November 2021, Northwestern University researchers introduced an injectable new therapy, which harnessed fast-moving "dancing molecules," to repair tissues and reverse paralysis after severe spinal cord injuries. Now, the same research...

By Kennedy Ferruggia - Pharmacy Times - The FDA has granted regenerative medicine advanced therapy (RMAT) designation for AIC100 (Affylmmune Therapeutics), an ICAM-1 targeting and affinity-tuned LFA-1 binder chimeric antigen receptor (CAR) T-cell therapy product...

By Riken Research News - RIKEN researchers have uncovered how gradual changes in gene-expression patterns drive a cell-fate switch in neural stem cells (NSCs) in mice1. All the major neuronal types of cells in the central nervous system are created through the...

By University of Geneva - Acute myeloid leukaemia is one of the deadliest cancers. Leukaemic stem cells responsible for the disease are highly resistant to treatment. A team from the University of Geneva (UNIGE), University Hospital of Geneva (HUG), and Inserm has...