News and Opinions
Dublin Longevity Declaration Off to a Good Start
by Arkadi Mazin - Lifespan.io The need for a paradigm shift Last August, hundreds of longevity enthusiasts, from certified geroscience stars to graduate students, gathered in Dublin for the annual Longevity Summit conference. As the attendants were enjoying the...
Three people were gene-edited in an effort to cure their HIV. The result is unknown.
By Antonio Regalado - MIT Technology Review The gene-editing technology CRISPR has been used to change the genes of human babies, to modify animals, and to treat people with sickle-cell disease. Now scientists are attempting a new trick: using CRISPR to permanently...
Douglas Melton Recognized for Pioneering the Process of Converting Stem Cells into Insulin-Producing Beta Cells
By UMass Chan Medical School The UMass Chan Diabetes Center of Excellence (DCOE) congratulates Doug Melton, PhD, who was awarded the Doctor Juan Abarca International Award for Medical Sciences for pioneering the process of converting stem cells into insulin-producing...
Researchers Develop Novel Genome Editing Software That Is Safer Than CRISPR
by Technology Networks A team of researchers has developed a software tool called DANGER (Deleterious and ANticipatable Guides Evaluated by RNA-sequencing) analysis that provides a way for the safer design of genome editing in all organisms with a transcriptome. For...
New wound healing research by Wake Forest Institute for Regenerative Medicine produces full thickness human bioprinted skin
By Atrium Health Wake Forest Baptist - EurekAlert News WINSTON-SALEM, NC – October 4, 2023 - A research paper published today in Science Translational Medicine presents a significant breakthrough in the area of skin regeneration and wound healing by researchers at...
Zooming in on rare bone cells that drive osteoporosis
By Mayo Clinic's Research Magazine Mayo Clinic researchers have developed a new high-resolution, analytical technique to identify the rare senescent bone cells that are known to drive osteoporosis. Senescent cells are malfunctioning cells that build up as people age...
Most of today’s gene therapies rely on viruses — and that’s a problem
By Tina Hesman Saey - Science News CRISPR and new approaches to delivery may help treat rare diseases In 2018, Will Ungerer, shown with doctor Jerry Mendell at Nationwide Children’s Hospital in Columbus, Ohio, received experimental gene therapy for Duchenne muscular...
Gene Transfer Leads to Longer Life and Healthspan
By Eve Herold - Director at HSAC - Published by Leaps.org In August, a study provided the first proof-of-principle that genetic material transferred from one species to another can increase both longevity and healthspan in the recipient animal. The naked mole rat...
An mRNA drug reengineers stem cells
by Samantha Borje - Drug Discovery News Scientists developed an alternative to bone marrow transplantation by using technology similar to that of the COVID-19 mRNA vaccines. Blood disorders such as sickle cell anemia, immunodeficiencies, and bone marrow failure...
UCLA-led team finds a stem-cell derived mechanism that could lead to regenerative therapies for heart damage
By Enrique Rivero - UCLA Health A UCLA-led team has identified an essential internal control mechanism that can promote the maturation of human stem cell-derived heart muscle cells, offering a deeper understanding of how heart muscle cells develop from their immature...
N.Y. State’s first cell and gene therapy hub coming to Roswell Park
By Adam Penale - Spectrum News New York state's first cell and gene therapy hub is coming to Roswell Park Comprehensive Cancer Center, Gov. Kathy Hochul announced Friday. State officials say the $98 million cell and gene therapy manufacturing facility in Buffalo will...
Scientific leaders issue global Dublin Longevity Declaration
By Eleanor Garth - Longevity.Technology Consensus recommendation to immediately expand research on extending healthy human lifespans. The Longevity Escape Velocity Foundation (LEVF) has welcomed the publication today of the Dublin Longevity Declaration. This...
Scientists have bioprinted fully functional human skin
By Chrissy Sexton - Earth.com For the first time, scientists have successfully bioprinted fully functional skin. Researchers at the Wake Forest Institute for Regenerative Medicine report that they have printed skin samples containing all six major cell types found in...
Nobel Prize in medicine won by two scientists for ‘groundbreaking findings’ on mRNA Covid-19 vaccines
By Christian Edwards, Katie Hunt and Ed Upright, CNN This year’s Nobel Prize in physiology or medicine has been awarded to Katalin Karikó and Drew Weissman for their work on mRNA vaccines, a crucial tool in curtailing the spread of Covid-19. The Nobel Prize committee...
Stem cell therapy to slow progression of multiple sclerosis (MS)
By Taylor Mixides - Drug Target Review Autologous haematopoietic stem cell transplantation (aHSCT), a medical procedure typically employed in the treatment of blood cancers, holds promise as a potential therapy for individuals with relapsing-remitting multiple...
Healthspan Action Coalition Endorses the Dublin Longevity Declaration
Wellington, FL, October 9, 2023—On October 3, 2023, the Longevity Escape Velocity Foundation released its historic Dublin Longevity Declaration, a groundbreaking document addressing one of humanity’s most pressing needs: extending healthy longevity for all humankind....
CIRM approves new plan to invest $110 million into basic research in neuropsychiatric diseases
The California Institute for Regenerative Medicine, the world’s largest institute dedicated to regenerative medicine, announced its approval of a new program called ReMIND at the September Independent Citizens Oversight Committee (ICOC) meeting that will eventually...
The Dublin Longevity Declaration
Scientific Leaders Issue global “Dublin Longevity Declaration” Consensus Recommendation to Immediately Expand Research on Extending Healthy Human Lifespans SAN FRANCISCO, CA, October 3, 2023—The Longevity Escape Velocity Foundation (LEVF) welcomes the publication...
Stanford University Aims to Bioprint a Human Heart and Implant It In a Pig
by CardioVascular Learning Network Under a new $26.3 million federal contract from the Advanced Research Projects Agency for Health (ARPA-H), a multidisciplinary team of researchers at Stanford University aims to bioprint a fully functioning human heart and implant it...
International Longevity Day and a Death-Defying Congressional Caucus
OPINION By Edward Hudgins There are over 200 congressional caucuses sharing economic, ideological, and every imaginable interest. Some have only a few members. But the new bipartisan Longevity Science Caucus, co-founded by Congressmen Gus Bilirakis (R-FL) and Paul...
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