News and Opinions
Stem cell therapy for interstitial cystitis/bladder pain syndrome
By PubMed - The analysis on phase 1/2a trial which had several modifications in protocol is currently ongoing. Despite several limitations that need to be overcome, stem cell therapy could be a potential therapeutic option for treating IC/BPS. Clinical outcome on...
Stem Cell Therapy Development Embraces New Technologies
By Genetic Engineering and Biotechnology News - Stem cell research recently celebrated its 60th anniversary. Although the first publications in this field appeared in the early 1960s, it took another 20 years before the first embryonic stem cells could be isolated....
Fertility treatments could get a boost from stem cells
by University of Copenhagen - MedicalXpress - An unexpectedly versatile and regenerative stem cell in early embryos may be key to creating new effective fertility treatments, suggests a new study in mice from the University of Copenhagen. The paper, titled "The...
Huntington Disease Gene Therapy Nets RMAT Designation
By Victoria Johnson - CGT Live = The FDA has granted Regenerative Medicine Advanced Therapeutic (RMAT) Designation to uniQure’s AMT-130 gene therapy for the potential treatment of Huntington disease (HD).1 “We’re thrilled to receive the first ever RMAT designation for...
Lab-grown muscles reveal mysteries of rare muscle diseases
By Duke University - Science Daily - Biomedical engineers at Duke University have developed a new technique to better understand and test treatments for a group of extremely rare muscle disorders called dysferlinopathy or limb girdle muscular dystrophies 2B (LGMD2B)....
Stem Cell Plasticity: A Double-Edged Sword
by Hannah Thomasy, PhD - The Scientist - Yejing Ge explores the behavior of skin-resident stem cells in wound repair, cancer, and aging. In 1986, Harold Dvorak, a pathologist at Harvard Medical School, popularized the idea of cancer as a wound that does not heal. In...
Unraveling the Mysteries of Stem Cells
By Gret Harrison - USC Viterbi - New research harnesses machine learning and imaging to give unprecedented insight into stem cell behavior that could enable future lifesaving therapies. Stem cells are like the emergency tool kit of the human body. They have the unique...
A vision of the future: Stem cells offer hope for retinal degeneration
By Hannah Thomasy, PhD - Exploring Drug Discovery and Development News - The black rat rested calmly in a clear tube, its nose twitching gently as it sniffed the air. Its eyes followed the parade of vertical black and white bars scrolling from left to right across a...
What New Gene Therapy Means For Sickle Cell Patients
Dr. Omer Awan MD MPH CIIP - Forbes - Recently, a 12-year-old boy became the first patient with sickle cell disease to begin commercially approved gene therapy that could potentially cure the condition. Read the article - Click Here
Computer-designed proteins guide stem cells to form blood vessels
by Ian Haydon, University of Washington School of Medicine - Phys.org - Using computer-designed proteins, researchers have now shown they are able to direct human stem cells to form new blood vessels in the lab. This milestone in regenerative medicine offers new hope...
Most stem cells die after being injected into brain; new technique could change that
By Laurie Kaiser - University of Buffalo - When the myelin sheath that surrounds nerve fibers in the brain and spinal cord becomes damaged, a number of debilitating conditions can result that limit mobility, inhibit independence and reduce life expectancy. Multiple...
FDA Grants Regenerative Medicine Advanced Therapy Designation for AMT-130 Gene Therapy in Huntington Disease
by Isabella Ciccone, MPH - Nueurology Live - Recently, the FDA granted regenerative medicine advanced therapy (RMAT) designation to uniQure’s investigational Huntington disease (HD) gene therapy AMT-130 based on interim data from a phase 1/2 trial (NCT04120493) and a...
L’Oreal says it’s working on a form of bioprinted skin that can actually ‘feel’
By Ryan Browne - CNBC - PARIS, France — French beauty and cosmetics giant L'Oreal is working on a form of synthetically produced skin that it says will one day be able to "feel" like we do. At the Viva Technology conference in Paris last week, L'Oreal showed off...
Study: CAR T for Prostate Cancer Shows Efficacy
by Letisia Marquez - City of Hope - Treating prostate cancer with immunotherapy is currently difficult to do. But preliminary results from a first in-human phase 1 trial using a chimeric antigen receptor (CAR) T cell therapy developed by researchers from City of Hope®...
A cell therapy to heal a broken heart
by Alejandra Manjarrez, PhD - Drug Discovery News - Researchers harvest stem cells from patients who have recently had a heart attack and use them to trigger regeneration of their cardiac muscle. For many people, surviving a heart attack is just the beginning. Within...
Japan startup to seek approval for iPS cell therapy in global first
by YUTA MAEDA - Nikkei - TOKYO -- A Japanese startup is poised to become the first in the world to seek government approval for a therapy derived from human induced pluripotent stem (iPS) cells, Nikkei has learned, with a less invasive alternative for treating heart...
Mistaken Identity: Gut Stem Cell Discovery Could Transform Regenerative Medicine
By NeuroscienceNews.com - Two studies reveal that scientists have misidentified gut stem cells, impacting research and treatments for 15 years. Researchers identified the true stem cells in a different gut region, which could lead to breakthroughs in regenerative...
New Webinar: Novel Interventions for Preempting Neurodegeneration
by The Kitalys Institute - FRIDAY JUNE 14, 2024 Co-Moderators Lee Rubin, PhD, Professor of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute and Lawrence Steinman, MD, Zimmermann Professor of Neurology & Neurological Sciences, and Pediatrics Stanford...
Disc comfort: gene therapy for chronic back pain
by Megan Giboney - RegMedNet - Ohio State University (USA) researchers have developed a novel non-viral gene therapy to treat discogenic back pain, a type of chronic low back pain that results from the degeneration of intervertebral discs. Intervertebral discs...
June 11 -13, 2024: Regenerative Medicine Essentials Course at Wake Forest Institute for Regenerative Medicine
By The Wake Forest Institute for Regenerative Medicine (WFIRM) Winston-Salem, North Carolina - The 11th annual Regenerative Medicine Essentials Course will again be held in Winston-Salem, North Carolina with both hybrid and in-person options. RME is the official...
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