News and Opinions

By Mayo Clinic's Discovery's Edge Mayo Clinic researchers and collaborators have identified a protein expressed by immune cells that may play a key role in the development of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. The team also found...

By Gina Kolata – The New York Times The first treatment that relies on CRISPR is expected to receive U.S. approval next month. But it may cost millions of dollars per patient. Regulators in Britain on Thursday approved the first treatment derived from CRISPR, the...

By News Medical Life Sciences Researchers from the Critical Analytics for Manufacturing Personalized-Medicine (CAMP) Interdisciplinary Research Group (IRG) of Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in...

By Andrew Schulman - Technology Networks Why do we need allogeneic therapies when autologous therapies have enjoyed such success? The lessons learned from the development and manufacture of autologous cell therapies are helping lay a solid groundwork for the high...

By Meghan Bartels - Scientific American Scientists have just achieved a milestone in stem-cell biology after creating a monkey from two embryos. And proof of the achievement, perhaps unnervingly, showed up in the infant primate’s eerie green glow. Although research...

by Sarah C.P. Williams, UCLA  - Phys.org News Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA are one step closer to developing stem cell therapies to regenerate skeletal muscle in humans. Working in mice, the...

by Tristan Epps - Penn Medicine News Ben Stanger, MD, PhD is a practicing Gastroenterologist at Penn Medicine. He is also the Hanna Wise Professor in Cancer Research and professor of Medicine and Cell and Developmental biology at the University of Pennsylvania....

Mayo Clinic researchers have identified new scoring criteria allowing for the detection of treatable forms of rapidly progressive dementia (RPD) with reasonably high confidence during a patient's first clinical visit. This scoring criteria may allow physicians to...

By Reuters News Oct 31 (Reuters) - A panel of advisers to the U.S. health regulator said on Tuesday Vertex Pharmaceuticals (VRTX.O) and CRISPR Therapeutics (CRSP.BN) could assess potential safety risks of their sickle cell disease gene therapy after approval. If the...

By Japan Times A Japanese medical institution, in a first for the country, will seek government approval for using embryonic stem cells as a regenerative medicine product to treat babies with a severe liver ailment, sources close to the matter said Monday. The step...

By Kyushu University Fukuoka, Japan – Researchers at Kyushu University have discovered that turning brain immune cells into neurons successfully restores brain function after stroke-like injury in mice. These findings, published on October 10 in PNAS, suggest that...

by Arkadi Mazin -  Lifespan.io The need for a paradigm shift Last August, hundreds of longevity enthusiasts, from certified geroscience stars to graduate students, gathered in Dublin for the annual Longevity Summit conference. As the attendants were enjoying the...

By Antonio Regalado - MIT Technology Review The gene-editing technology CRISPR has been used to change the genes of human babies, to modify animals, and to treat people with sickle-cell disease. Now scientists are attempting a new trick: using CRISPR to permanently...

By UMass Chan Medical School The UMass Chan Diabetes Center of Excellence (DCOE) congratulates Doug Melton, PhD, who was awarded the Doctor Juan Abarca International Award for Medical Sciences for pioneering the process of converting stem cells into insulin-producing...

by Technology Networks A team of researchers has developed a software tool called DANGER (Deleterious and ANticipatable Guides Evaluated by RNA-sequencing) analysis that provides a way for the safer design of genome editing in all organisms with a transcriptome. For...

By Atrium Health Wake Forest Baptist - EurekAlert News WINSTON-SALEM, NC – October 4, 2023  - A research paper published today in Science Translational Medicine presents a significant breakthrough in the area of skin regeneration and wound healing by researchers at...

By Mayo Clinic's Research Magazine Mayo Clinic researchers have developed a new high-resolution, analytical technique to identify the rare senescent bone cells that are known to drive osteoporosis. Senescent cells are malfunctioning cells that build up as people age...

By Tina Hesman Saey - Science News CRISPR and new approaches to delivery may help treat rare diseases In 2018, Will Ungerer, shown with doctor Jerry Mendell at Nationwide Children’s Hospital in Columbus, Ohio, received experimental gene therapy for Duchenne muscular...