News and Opinions
Greenstone Bio Secures $1.3M from CIRM for iPSC-derived Cardiovascular Cell Technologies
By By Cade Hildreth, BioInformant Palo Alto, CA – Greenstone Biosciences, Inc. (“Greenstone Bio”), a commercial-stage computational biology company, announces that the Company has received a DISC0 grant funding from the California Institute of Regenerative Medicine...
Second death linked to potential antibody treatment for Alzheimer’s disease
By Charles Piller - Science image caption: There are two hallmarks of Alzheimer’s dementia, amyloid-beta protein deposits known as plaques among brain cells (yellow-orange bundles), and tangles of a protein called tau inside neurons (wiry objects inside the neuron),...
A cell biologist shares the wonder of researching life’s most fundamental form
By Terry Gross - NPR news Dr. Siddhartha Mukherjee still remembers the first cell he cultured: It was an immune cell from a mouse, and he had grown it in a petri dish. As he examined it through a microscope, the cell moved, and Mukherjee was fascinated. "I could...
Biologists Create a New Type of Human Cells
The new model cells aid in the study of early embryonic development. by KU Leuven - SciTechDaily Professor Vincent Pasque and his colleagues at KU Leuven have used stem cells to create a new kind of human cell in the lab. The new cells closely mirror their natural...
Stem Cell Transplant May Halt Nerve Fiber Damage in RRMS: Study
Markers of nerve damage fell significantly in most patients after transplant by Marisa Wexler - Multiple Sclerosis News Today Autologous hematopoietic stem cell transplant (aHSCT) reduces markers of nerve fiber and myelin damage in people with relapsing-remitting MS...
FDA creates “Super Office” to manage growing cell and gene therapy workload
By Greg Slabodkin, ScienceBoard Editor in Chief The U.S. Food and Drug Administration (FDA) has elevated and reorganized its Office of Tissues and Advanced Therapies (OTAT) to a “Super Office” within the Center of Biologics Research and Evaluation (CBER) to meet its...
A Bold Effort to Cure HIV—Using Crispr
An experiment tests whether the gene-editing technology can stop the virus from replicating, which would ultimately wipe out the infection. By Wired.com In July, an HIV-positive man became the first volunteer in a clinical trial aimed at using Crispr gene editing to...
Ancient disease has potential to regenerate livers, study finds
University of Edinburgh - Eurekalert.org Leprosy is one of the world’s oldest and most persistent diseases but the bacteria that cause it may also have the surprising ability to grow and regenerate a vital organ. Scientists have discovered that parasites associated...
Sierra Space and UC San Diego to develop first stem cell research institute in space
By Jim Cornall - Labiotech.eu Sierra Space and University of California San Diego, one of the world’s top 15 research universities and a leader in microgravity research, have formed a new agreement with the goal of defining the future of human health care research in...
For the First Time Ever, People Are Getting Transfusions of Lab-Grown Blood Cells
UK scientists have begun the first clinical trial of lab-grown red blood cells, with the hope that they survive longer in volunteers than donated blood cells. By Ed Cara - Gizmodo An important clinical trial is now underway in the UK. The study is the first to...
How horseshoe crab blood became one of the most valuable liquids in medicine
By Bill Schutt - Big Think The crabs' blue blood contains an ancient immune defense mechanism that has helped save countless human lives. The story of the Atlantic horseshoe crab’s first turn toward medical relevance occurred in 1956. That’s when Woods Hole...
Three Noteworthy Applications of CRISPR
By Demaris Mills, Integrated DNA Technologies - Technology Networks Only 10 years ago, Nobel prize-winning work introduced CRISPR, or clustered regularly interspaced short palindromic repeats, as a new and powerful genome editing tool. Since then, many exciting...
FDA approves first ALS drug in 5 years after pleas from patients
The treatment was thought up by two Brown University undergraduates a decade ago. By Laurie McGinley - The Washington Post The Food and Drug Administration on Thursday overcame doubts from agency scientists and approved a fiercely debated drug for ALS, a move that...
Stem Cell Grafts and Rehabilitation Combined Boost Spinal Cord Injury Results
By UC San Diego Today In animal models, researchers found that intensive physical therapy in tandem with implanted neural stem cells increased tissue growth, repair, and functionality more than those treatments alone In recent years, researchers have made measurable...
Reactive Oxygen Species Found to Play Key Role in Stem Cell Function
By University of Oxford - Genengnews.com Scientists at Mount Sinai say they have published one of the first studies to demonstrate the importance of reactive oxygen species in maintaining stem cell function and preventing inflammation during wound repair. The team...
How an experimental treatment beat a little girl’s cancer
CBS Sunday Morning Emily Whitehead has a secret weapon: "My T-cells, part of my immune system, were trained to fight and kill my cancer." She was only six when she became the first child ever to receive genetically-modified T cells. The experimental treatment cured...
World’s first stem cell treatment for spina bifida delivered during fetal surgery
Brilliant and inspiring article! Stem cell treatment for spina bifida! For the first time in the world, #UCDavisHealth successfully cured #paralysis and predicted associated neurological defects spina bifida for babies in utero during fetal surgery. Kudos to fetal...
New Treatment Target Could Counter Bone Loss
By University of Pennsylvania - Sci Tech Daily Overactive populations of osteoclasts may result in a variety of disorders such as osteoporosis, arthritis, and cancer. A new function for a protein that regulates osteoclasts—the cells that break down bone—has been...
Experimental umbilical cord stem cell therapy treats rare disease
A girl with a rare disorder can now breathe more easily after receiving transfusions of a liquid that her sister's umbilical cord stem cells were grown in By Clare Wilson - New Scientist A girl who was critically ill with heart failure is doing well after receiving an...
Chinese scientists find axolotl’s ability to regenerate after injury may hold key to human brain health
Image caption: Chinese scientists whose study of the axolotl’s ability to regenerate cells after injury was published in Science journal say their findings have the potential to help improve the regenerative capability of mammalian and human brains in the future....
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