News and Opinions
Novel surgical approach for retinal gene therapy shows promise
By Mayo Clinic - A Mayo Clinic study published in the September 2025 issue of Science Advances explores a novel approach to retinal gene therapy using fibrin hydrogels encapsulating adeno-associated virus 2-green fluorescent protein (AAV2-GFP). The findings suggest a...
The Best Biomarkers For Longevity, According To Experts
By Heidi Borst - Forbes - Human longevity has reached new heights. During the 20th century, lifespan in high-income countries increased by about 30 years due to public health and medicine advancements, according to a 2024 analysis in Nature Aging.[1] In the U.S., the...
Regeneron’s experimental therapy combo effective in untreated cancer patients
By Sriparna Roy - Reuters News - Regeneron (REGN.O), opens new tab said on Saturday its experimental cancer combination therapy was effective and showed disappearance of the disease in previously untreated patients with a type of blood cancer in the first part of a...
The quest to slow aging leads scientists into the powerhouse of cells
by Mark Johnson - MSN - Aging taps us on the shoulder in many ways: wrinkles, thinning hair, loss of flexibility, slowing of the brain. But the process also unfolds at a more fundamental, microscopic level, as the energy source inside most cells deteriorates....
Disarming cancer stem cells’ shield makes immunotherapy more effective
by UChicagoMedicine - Immunotherapy has revolutionized cancer care by training the immune system to detect and destroy tumors. For many patients, it works very well in shrinking tumors and sending cancer into remission, an undetectable state of cancer. But that...
Vycellix Prepares for First-in-Human Study of Novel Allogeneic Cell Therapy Powered by Its Universal Cell Engineering Platform
By Vycellix - - Single-step CD45-engager technology shows robust immune evasion with functional persistence in pre-clinical models - Phase 1 study to evaluate ‘off-the-shelf’ natural killer cell cancer immunotherapy in the treatment of multiple myeloma BOCA RATON,...
Crispr gene-editing technology offers new hope for HIV cure but faces delivery challenges
By Tosin Thompson - Chemistry World - Two years ago, the UK became the first country to approve Casgevy, a Crispr-based therapy for the blood disorders sickle cell disease and β-thalassaemia. This year saw the world’s first personalised Crispr therapy for a baby boy...
CRISPR Gets an Invisibility Cloak
By Technology Networks - Scientists created an immunity-proof CRISPR system that reveals hidden metastasis genes in mouse tumour models. The immune system plays a crucial role in fighting tumours and metastases. Consequently, it is decisive to conduct cancer research...
The vital, overlooked role of body fat in shaping your health and mind
By Linda Geddes - NewScientist - f you melted down the average UK adult, you’d find around 22 kilograms (48.5 pounds) of creamy yellow fat – equivalent to around 88 blocks of lard, enough to fill two-thirds of a small suitcase or cast into 446 dinner candles. Melted,...
Nanoflowers rejuvenate old and damaged human cells by replacing their mitochondria
by James Cavin - Phys.org - Biomedical researchers at Texas A&M University may have discovered a way to stop or even reverse the decline of cellular energy production—a finding that could have revolutionary effects across medicine. Dr. Akhilesh K. Gaharwar and...
The world’s first personalized gene therapy
By Cold Spring Harbor Laboaratory - How does science make life better? Here’s one example spanning eons. There’s an adaptive immune system called CRISPR that has existed in bacteria for billions of years. Thanks to fundamental biology research, it is now being used to...
Bone Marrow Model Created Entirely from Human Cells
By Genetic Engineering and Biotechnology News - Typically, bone marrow research relies heavily on animal models and oversimplified cell cultures in the laboratory. Now, researchers from the Department of Biomedicine at the University of Basel and University Hospital...
Inflammation turns bone marrow into a breeding ground for disease
By Science Daily - Inflammation covertly rewires the bone marrow, enabling mutated stem cells to rise and setting the stage for future blood disease. Researchers discovered that chronic inflammation fundamentally remodels the bone marrow, allowing mutated stem cell...
Artificial intelligence and systems biology analysis in stem cell research and therapeutics development
By Stem Cells Translational Medicine - Background: Stem cell research has rapidly advanced during the past decades, but the translation into approved clinical products is still lagging behind. Multiple barriers to effective clinical translation exist. We hypothesize...
The resurgence of mesenchymal stem cell therapies
By Miranda McLaren - Clinical Trials Alerts - Mesenchymal stem cells have been explored across a wide range of diseases due to their potential to reduce inflammation and promote tissue repair and regeneration. BBG Advanced Therapies’ Rogelio Zamilpa, PhD takes us...
New nanotech method loads stem cells with extra mitochondria to recharge dying cells
by Aamir Khollam - Interesting Engineering - Texas A&M scientists used nanoflower-boosted stem cells to deliver extra mitochondria to weakened cells, restoring lost energy and improving survival under stress. Scientists at Texas A&M University say they may have found...
Scientists use stem cells to model rare genetic blindness in children
by Children's Medical Research Institute - MedicalXpress - Researchers at the Eye Genetics Research Unit at Children's Medical Research Institute (CMRI) are the first in the world to use stem cells to study one of the genetic causes of Leber Congenital Amaurosis...
We need to start thinking of AI as “normal”
By James O'Donnell - MIT Technology Review - As technologists frame AI as either utopian or dystopian, two researchers offer a third option. Right now, despite its ubiquity, AI is seen as anything but a normal technology. There is talk of AI systems that will soon...
Stem Cells Prevent Heart Failure After Heart Attack
By American Medical Journal - A NEW phase 3 clinical trial has revealed that stem cells can help prevent heart failure in patients recovering from acute myocardial infarction. The study found that intracoronary infusion of mesenchymal stem cells significantly reduced...
Engineered Bone Marrow Model Advances CRISPR-CAR T Research in AML
By Genetic Engineering and Biotechnology News - Scientists at the University of Glasgow developed a bioengineered bone marrow (BM) model that helped them to evaluate potential use of a combined CRISPR-CAR T cell therapy in the treatment of acute myeloid leukemia. The...
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