News and Opinions
Barcelona Biobank Gets Grant To Research Stem Cell Reprogramming in Wild Animals
By Technology Networks - The Barcelona CryoZoo aims to safeguard and study biological material from a wide range of animal species. The Barcelona CryoZoo is a one-of-a-kind project aiming to safeguard and study biological material from a wide range of animal species –...
Trained human bone marrow mesenchymal stem cells restore tissue immuno-microenvironment in fulminant hepatic failure mice
By BMC - Part of SpringerNature - Trained immunity with human bone marrow mesenchymal stem cells (hBMSC) is a promising approach to liver regeneration. This study aimed to clarify the trained-hBMSC (T-hBMSC) in restoring tissue immuno-microenvironment in fulminant...
ARPA-H data chief departs over disagreement with mRNA vaccine rollback
By Darren Incorvaia - Fierce Biotech - After the Department of Health and Human Services canceled about $500 million in funding for mRNA vaccine development, one senior agency leader has decided to call it quits. Alastair Thomson is resigning as chief data officer at...
VA’s first bloodless stem cell transplant leads to Veteran’s cancer remission
By Abby Woodruff - Veterans Affairs - Earlier this year, VA Tennessee Valley Healthcare System (TVHS) performed the first-ever bloodless autologous stem cell transplant in the VA system. Keith Cody, a Marine Corps Veteran, walked out of TVHS in remission and caught a...
Study using stem cells created from ALS patients identifies potential new target for treatment
by Case Western Reserve University - The Daily - CLEVELAND—Amyotrophic lateral sclerosis (ALS), known as Lou Gehrig’s disease, is an incurable neurological disorder affecting motor neurons—nerve cells in the brain and spinal cord that control voluntary muscle movement...
Uncertainty clouds the San Diego biotech hub, with jobs and capital scarce
By Jonathan Wosen - Stat - But optimism pokes through, as VC returns and local biotech stocks have fared well Ever since Vince Kato was laid off, he has felt like he was just two to three months away from landing a new position. But more than a year later, he’s...
Top FDA Official’s Surprise Departure Means More Uncertainty for Biotech
By Josh Nathan-Kazis - Barron's - Biotech investors seemed to be taking the sudden departure of a top Food and Drug Administration official last month as a good sign for the sector, but increasing turmoil at the FDA could worsen the picture for drugmakers over the...
RFK Jr. Cancels $500 Million In Federal Funding For mRNA Vaccine Research
By Siladitya Ray - Forbes - Health and Human Services Secretary Robert F. Kennedy Jr. announced he is cancelling contracts and grants worth nearly $500 million earmarked to develop mRNA vaccines, as the long-time vaccine critic has repeatedly cast doubts about the...
Mayo Clinic treats first person in the US with a novel radiopharmaceutical therapy for breast cancer
by Brittany Cordeiro - Mayo Clinic - ROCHESTER, Minn. — Mayo Clinic has treated the first person in the U.S. using a novel radioactive medicine for advanced breast cancer as part of an international multisite clinical trial. The medicine used in this clinical trial...
Slashing NIH funding imperils the foundation of medical research
By Bobby Mukkamala, MD - AMA - For more than a century, NIH-sponsored research has played a critical role in improving the nation’s health. This vital work must continue. It’s not hyperbole to say my sudden brain cancer diagnosis last fall could have put a swift end...
Designer Stem Cells Power New R&D Assay Systems
by By Kathy Liszewski - Genetic Engineering & Biology News - Novel allogeneic stem cells and differentiated iPSCs are providing more physiologically relevant disease models From axolotls to zebrafish, stem cells possess remarkable regenerative abilities, enabling them...
Scientists reprogram stem cells to create renewable cancer-fighting T cells
by Denise Heady, University of California, Los Angeles - MedicalXpress - In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune...
Stem cell therapy found to boost fertility in women with ovarian failure
By Celeste Krewson - Contemporary OB/GYN - Stem cell treatment may be effective for fertility restoration in women with ovarian failure, according to a recent study published in Aging (Aging-US).1 This method was associated with a 70% oocyte activation rate and...
The pandemic aged our brains, whether we got Covid or not, study find
By Linda Carroll NBC News - Brain aging may have sped up during the pandemic, even in people who didn’t get sick from Covid, a new study suggests. Using brain scans from a very large database, British researchers determined that during the pandemic years of 2021 and...
Sarepta fails to win EU backing for muscle disorder gene therapy
By Christy Santhosh - Reuters News - Sarepta Therapeutics (SRPT.O), failed to win the European drug regulator's backing for its muscle disorder gene therapy on Friday, as the company faces intense regulatory scrutiny after two recent patient deaths tied to the...
Adipose-derived mesenchymal stromal/stem cells in type 1 diabetes treatment
By Nature Communications Biology - Adipose tissue-derived mesenchymal stromal/stem cells (ADMSCs) represent a novel therapeutic intervention for Type 1 Diabetes (T1D). The attractiveness of ADMSCs is characterized by their immunomodulatory activities, regenerative...
Novel, Less Toxic, Stem Cell Transplant Prep Yields Successful Outcomes
By Genectic Engineering & Biotechnology - Phase I clinical trial results suggest that an antibody treatment, used in combination with other drugs, enabled stem cell transplants for three children with Fanconi anemia without toxic busulfan chemotherapy or radiation....
Florida Is Now a Haven for Unproven Stem-Cell Treatments
By Emily Mullin - WIRED - Florida is the latest state to sidestep the authority of the Food and Drug Administration by allowing patients to access certain stem-cell treatments that have not been rigorously evaluated and approved. Under a new law that went into effect...
Engineering immune cells within the body
By National institutes of Health - Chimeric antigen receptor (CAR) T cell therapies involve taking immune cells, called T cells, from a patient and engineering them to make a protein that lets them recognize and attack the patient’s cancer cells. CAR T cells have...
We need new regulation to keep up with longevity innovation
By Danny Sullivan - Longevity.Technology - Healthspan Action Coalition's Bernard Siegel says new state laws show the federal government needs to ‘get its act together’ on patient access to innovative therapies. As a member of the Florida Bar Association for the past...
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