News and Opinions
US researchers develop new bioreactor for enhanced stem cell growth
By Ada Shaikhnag - 3D Printing Industry News - Researchers from Los Alamos National Laboratory (LANL) have developed a 3D printed perfusion bioreactor (3D-PBR) created to improve how human bone marrow-derived mesenchymal stem cells (MSCs) grow and differentiate. With...
Combination immunotherapy shrank a variety of metastatic gastrointestinal cancers
by National Cancer Institute (NCI) - NIH trial shows new form of TIL therapy effective against colon, rectum, pancreas, and bile duct tumors. A new form of tumor infiltrating lymphocyte (TIL) therapy, a form of personalized cancer immunotherapy, dramatically improved...
Molecular Pathways in Bone Marrow Stem Cell Senescence
By Physician's Weekly - Researchers conducted a retrospective study to analyze miRNA-mRNA regulatory networks influencing bone marrow mesenchymal stem cell (BMSCs) senescence in age-related osteoporosis (ARO), aiming to determine molecular markers and therapeutic...
Treating spinal cord injuries with stem cells
PODCAST by Brian Culley - Beyond Biotech - Spinal cord injuries impact millions of people worldwide and, unlike many chronic injuries, they usually arrive with no forewarning, impacting the young and old alike. Brian Culley is CEO of Lineage Cell Therapeutics and his...
A new kind of stem cell is revolutionizing regenerative medicine
By Marissa Locke Rottinghaus - ASBMB Today - Regenerative medicine is rewriting the future of health care, with stem cells leading the charge as researchers report that their experimental induced pluripotent stem cell, or iPSC, therapeutics could restore vision and...
Paralysed man stands again after receiving ‘reprogrammed’ stem cells
By Smriti Mallapaty - Nature - Another man also regained some movement, but two others experienced minimal improvement. A paralysed man can stand on his own after receiving an injection of neural stem cells to treat his spinal-cord injury. The Japanese man was one of...
Cell and Gene Therapy Sector Sees 30% Investment Surge Despite Market Challenges
by BioSpace Insights - Industry updates and investment insights—including investor behavior and fundraising advice—were among the topics experts explored at Charles River Laboratories’ 2025 Cell & Gene Therapy Summit. With the cell and gene therapies (CGTs) sector...
Will Stem Cell Clinics Flourish Under RFK Jr.?
by Rachael Robertson MedPageToday - After HHS Secretary Robert F. Kennedy Jr. hosted a roundtableopens in a new tab or window on reducing regulations on stem cells earlier this month, experts have raised concerns about a potential flourishing of questionable stem cell...
Cells That Build Themselves Into an Embryo? Scientists Just Made It Happen
By University of California - Santa Cruz - SciTechDaily - Scientists have found a way to study early embryonic development without real embryos. Using CRISPR, they programmed stem cells to self-organize into structures mimicking early embryos. The cells show...
Healthspan Action Coalition and Kitalys Institute Propose Landmark Legislation to Promote Healthy Longevity
“An important step towards slowing aging and the onset of major age-related chronic diseases” Washington, DC and San Francisco, CA, March 27, 2025— The Healthspan Action Coalition (HSAC) and the Kitalys Institute jointly proposed today the initial draft of a bill...
Probing the Mysteries of the Aging Brain
By Dennis Nealon - Harvard Research - Research led by new faculty member Michael Segel focuses on mammalian lifespans Sixteen years ago, Michael Segel was a rising senior at Brookline High School in Massachusetts when, acting on a friend’s suggestion, he signed on for...
Building a regenerative medicine industry: Lessons from North Carolina
By Tim Bertram - Pharmaphorum - The field of regenerative medicine is advancing rapidly, offering transformative solutions for a wide range of health conditions. However, while scientific breakthroughs in regenerative medicines like cell and gene therapies continue,...
New CRISPR tool enables more seamless gene editing — and improved disease modeling
By Bill Hathaway - Yale Health & Medicine - Yale scientists have developed a CRISPR technology that can assess genetic interactions on a host of immunological responses to multiple diseases, including cancer. Advances in the gene-editing technology known as...
New CAR-T Cell Therapy Shows Promise for Hard-to-Treat Cancers
by Laura Kelley - University of Colorado Cancer Center - Researchers at CU Anschutz Medical Campus have developed ALA-CART, a next-generation therapy aimed at improving outcomes for patients with resistant cancers. “This next-generation approach, called ALA-CART...
Scientists create universal vascular graft with stem cells to improve surgery for cardiovascular disease
by Morgridge Institute for Research - MedicalXpress - Scientists at the Wisconsin National Primate Research Center (WNPRC) and the Morgridge Institute for Research at the University of Wisconsin–Madison have been at the forefront of stem cell research and regenerative...
Gene Therapy in an Implant: Neurotech Lands First FDA Approval in Rare Vision Disorder
By Frank Vinluan - MedCity News - Neurotech Pharmaceuticals’ surgically implanted cell and gene therapy, Encelto, is now FDA approved to treat macular telangectasia type 2 (MacTel). It’s the first therapy for this rare retinal degeneration disorder. Protein therapies...
Clinical Trial Tests Novel Stem-Cell Treatment for Parkinson’s Disease
By Mass General Brigham - A recently launched Phase 1 clinical trial at Mass General Brigham is examining the safety and feasibility of a groundbreaking treatment approach for Parkinson’s disease in which a patient’s stem cells are reprogrammed to replace dopamine...
Clinical Trial Tests Novel Stem Cell Treatment for Parkinson’s Disease
By Technology Networks - Reprogrammed stem cells to replace dopamine cells in the brain may offer hope for Parkinson's treatment. A recently launched Phase 1 clinical trial at Mass General Brigham is examining the safety and feasibility of a groundbreaking treatment...
Novel Stem Cell Therapy Repairs Irreversible Corneal Damage in Clinical Trial
By Mass General Brigham - An expanded clinical trial that tested a groundbreaking, experimental stem cell treatment for blinding cornea injuries found the treatment was feasible and safe in 14 patients who were treated and followed for 18 months, and there was a high...
Stem Cell Transplant for Wet Age-Related Macular Degeneration Clears Clinical Study
By Technology Networks - A new, alternative treatment for wet AMD involves the transplantation of stem cell-derived retinal cells. Age-related macular (AMD) degeneration is a leading cause of vision impairment and blindness in the elderly population. In so-called wet...
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