News and Opinions
Overview of the application of nanogels in wound healing
By Journal of Drug Delivery Science and Technology - Abstract Wound healing is the process of tissue regeneration, which, under normal conditions, is a very time-consuming process. It is also very susceptible to complications such as infection and chronic...
Key genetic characteristics of compatibility when transplanting blood cell-producing stem cells identified
by University of Geneva - MedicalXpress - Transplanting hematopoietic stem cells from healthy individuals is one of the possible treatments for blood cancers. In Switzerland, it involves nearly 300 patients per year. However, nearly half of transplants fail, mainly...
World’s first spinal cord transplant to take place in Israel, could allow patients to walk again
By PESACH BENSON/TPS - The Jerusalem Post - Tel Aviv University announced on Wednesday that the surgery will take place in Israel, marking a historic milestone in regenerative medicine. Israel is preparing to perform the world’s first-ever human spinal cord implant...
Stanford Breakthrough: Stem Cell Transplants Without Toxic Chemo or Radiation
By By Erin Digitale, Stanford Medicine - SciTechDaily - A Phase 1 clinical trial has shown that an antibody developed at Stanford Medicine can prepare patients for stem cell transplantation while avoiding toxic side effects. A phase 1 clinical trial has demonstrated...
Stopping time in cells exposes life’s fastest secrets
By The University of Osaka - Science Daily - Researchers from The University of Osaka develop time-deterministic cryo-optical microscopy, which freezes cells with millisecond precision, enabling accurate, high-resolution visualization of transient moments during...
Universal plug-and-play CAR-T cell therapy could transform cancer immunotherapy
by University of Chicago Medical Center - MedicalXpress - Researchers at the University of Chicago have developed a "universal" chimeric antigen receptor (CAR) platform that offers enhanced safety, adaptability, and the potential to overcome long-standing barriers in...
The Promise of Stem Cells: From Healing Hearts to Protecting Pandas
by Andrea Lius, PhD - The Scientist - Researchers bank on stem cells to study developmental biology, understand oral cancer, regenerate organs, and save species on the brink of extinction. Stem cells can self-renew and differentiate into a wide variety of cell types,...
USAMRIID scientists develop novel 3D bioprinted tissue model
by Quentin Johnson - dvidshub.net - FORT DETRICK, Md.– Scientists at the U.S. Army Medical Research Institute of Infectious Diseases have successfully created a novel 3D bioprinted vascular liver tissue model, marking a significant advancement in biomedical research...
Stem cell discovery could be key to healing tough-to-fix fractures
By Penn Medicine - The ability of a newly understood stem cell originating in skeletal muscle to turn into bone could hold the key to bone healing after catastrophic fractures. When bones break and there is extreme tissue loss—such as after a car accident or a...
In cell therapy, cost is a hot issue. The industry might need a cold solution.
by Michael Gibney - PharmaVoice - The first cell therapy approved by the FDA, Dendreon’s Provenge for prostate cancer, had a bumpy start on the market in 2010, as the autologous treatment was logistically difficult to manufacture and administer, and thus also to...
New activated cell therapy to treat osteoarthritis
By Sarah Nesbella - Colorado State University - Osteoarthritis (OA) affects over 550 million people worldwide, and there still aren’t effective treatments to stop the continued joint inflammation and cartilage destruction caused by OA. The lifetime likelihood of...
UCLA scientists develop off-the-shelf immunotherapy for ovarian cancer
By Linda Wang - UCLA Newsroom - Ovarian cancer is the leading cause of death among women with gynecological cancers. The current medical playbook — surgery followed by chemotherapy — initially shows promise. Tumors shrink, sometimes disappearing entirely. But in more...
Japan MHLW approves Biostar’s angel stem cell therapy for autism
By Pharmaceutical Technology News - Biostar Stem Cell Technology Research Institute has received the Japanese Ministry of Health, Labour and Welfare (MHLW) approval for its angel stem cell therapy for autism spectrum disorder (ASD). Biostar is jointly operated by RBIO...
Stem cell-derived dopamine neurons improve depression-like behaviors in mice
by Justin Jackson - Phys.org - MedicalXpress - The Institute of Neuroscience, Chinese Academy of Sciences, reports that human stem cell-derived A10-like midbrain dopaminergic neurons integrate into mouse mesocorticolimbic circuits and suppress anxiety and depression...
Barcelona Biobank Gets Grant To Research Stem Cell Reprogramming in Wild Animals
By Technology Networks - The Barcelona CryoZoo aims to safeguard and study biological material from a wide range of animal species. The Barcelona CryoZoo is a one-of-a-kind project aiming to safeguard and study biological material from a wide range of animal species –...
Trained human bone marrow mesenchymal stem cells restore tissue immuno-microenvironment in fulminant hepatic failure mice
By BMC - Part of SpringerNature - Trained immunity with human bone marrow mesenchymal stem cells (hBMSC) is a promising approach to liver regeneration. This study aimed to clarify the trained-hBMSC (T-hBMSC) in restoring tissue immuno-microenvironment in fulminant...
ARPA-H data chief departs over disagreement with mRNA vaccine rollback
By Darren Incorvaia - Fierce Biotech - After the Department of Health and Human Services canceled about $500 million in funding for mRNA vaccine development, one senior agency leader has decided to call it quits. Alastair Thomson is resigning as chief data officer at...
VA’s first bloodless stem cell transplant leads to Veteran’s cancer remission
By Abby Woodruff - Veterans Affairs - Earlier this year, VA Tennessee Valley Healthcare System (TVHS) performed the first-ever bloodless autologous stem cell transplant in the VA system. Keith Cody, a Marine Corps Veteran, walked out of TVHS in remission and caught a...
Study using stem cells created from ALS patients identifies potential new target for treatment
by Case Western Reserve University - The Daily - CLEVELAND—Amyotrophic lateral sclerosis (ALS), known as Lou Gehrig’s disease, is an incurable neurological disorder affecting motor neurons—nerve cells in the brain and spinal cord that control voluntary muscle movement...
Uncertainty clouds the San Diego biotech hub, with jobs and capital scarce
By Jonathan Wosen - Stat - But optimism pokes through, as VC returns and local biotech stocks have fared well Ever since Vince Kato was laid off, he has felt like he was just two to three months away from landing a new position. But more than a year later, he’s...
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