News and Opinions
UC San Diego Health among First in Nation to Perform Regenerative Brain Cell Procedure for Epilepsy
The new experimental cell therapy is part of a national clinical trial aimed at eliminating seizures By Annie Pierce - UC San Diego Today In what could lead to a revolutionary advancement in the treatment of temporal lobe epilepsy, UC San Diego Health has become one...
Pioneering Stem Cell Therapy Offers New Hope for Epilepsy Treatment
By Neuroscience.com Researchers embarked on a groundbreaking clinical trial involving the injection of regenerative cells into the brain to treat epileptic seizures. This experimental therapy, called NRTX-1001, has the potential to offer drug-resistant temporal lobe...
Gene therapy eyedrops restored a boy’s sight. Similar treatments could help millions
by LAURA UNGAR and FREIDA FRISARO - MedicalXpress Dr. Alfonso Sabater pulled up two photos of Antonio Vento Carvajal's eyes. One showed cloudy scars covering both eyeballs. The other, taken after months of gene therapy given through eyedrops, revealed no scarring on...
AI is transforming every aspect of science. Here’s how.
By Saikiran Chandha - Live Science In the future, research labs will embrace the transformative potential of artificial intelligence to tackle wicked problems and speed up scientific discovery. Scientific laboratories of the future probably won't have flying robots,...
Scientists find the key to potentially reversing Parkinson’s disease
by David McManus - Disability Support Guide A new breakthrough in Parkinson’s disease research has moved scientists one step closer to a significant treatment. Researchers were able to yield significant results through transplanting the skin cells of two people with...
Cell and gene therapy is coming of age
By Center for Breakthrough Medicine - BIOPHARMADIVE The enormous impact the pandemic had on the biopharma industry is unmistakable, as evidenced by the unprecedented investments that took place in the cell and gene therapy (CGT) space. In January 2022, the Milken...
Grow-your-own stem cells may repair Parkinson’s damage
By Bronwyn Thompson - New Atlas A new stem cell therapy for Parkinson’s disease is one step closer to human trials after scientists were able to successfully rebuild neural damage in an animal model. Researchers from Scripps Research and Cardiff University used...
Researchers turn to CRISPR to unlock one of the trickiest diseases to treat: Alzheimer’s
By Andrew Joseph - Stat News When the genome-editing tool CRISPR is thought of as a potential medicine, the targets that first come to mind are diseases like sickle cell or other conditions caused by particular mutations. Use CRISPR to fix that mutation, the idea...
The next genomics wave: The powerful era of single-cell genomics
By The Harvard Gazette For more than 20 years, scientists have been able to unravel the sequence of the human genome, the precise recipe of everyone’s DNA. That has led to incredible advances in discovering genes responsible for countless diseases. But within the last...
Researchers visualize activity of CRISPR genetic scissors in real time
by Leipzig University - Phys.org When bacteria are attacked by a virus, they can defend themselves with a mechanism that fends off the genetic material introduced by the intruder. The key is CRISPR-Cas protein complexes. It is only in the last decade that their...
Making Genetically Engineered Stem Cells Viable
Growing and selection are crucial. by Josh Conway - Lifespan.io CRISPR is still imperfect While the accuracy of genetic modification through the well-known CRISPR/Cas9 system continues to improve, the technology remains imperfect. Small mistakes were initially...
Stem Cell Medical Tourism Leads to Meningitis in MS Patient
— Difficult infection took weeks to identify; doctors warn about unproven treatments by Sophie Putka - MedPage Today A woman with multiple sclerosis (MS) who had intrathecal injections of umbilical cord stem cells in Mexico ended up with a severe Mycobacterium...
CAR T Cells Derived From Stem Cells Open Door To Universal Donor Cell Lines
by William A. Haseltine - Forbes Induced pluripotent stem cells (iPSC), a continuing muse in cell therapy research, could potentially be used to improve flaws associated with conventional CAR T therapy. What if an effective cancer treatment became cheaper and easier...
$3M grant allows milestone in regenerative medicine using blood vessels
By Izzy Wood - Drug Target Review US researchers combine revascularisation techniques to allow new blood vessels to rapidly form in an architecturally organised manner. The ability to regenerate and pattern blood vessels remains an elusive milestone in regenerative...
Stem Cell Model Points to Alzheimer’s Disease Embryonic Origins
By Genetic and Engineering News Alzheimer’s disease (AD) is the sixth leading cause of death in the United States. However, the exact cause of AD remains unknown. Existing approved treatments for AD are designed to target the already existing AD neuropathology,...
A Fast, Effective Way to Detect Cancer Stem Cells
By McMaster University McMaster researchers have uncovered a fast and effective way to detect cancer stem cells before the disease recurs in adults who previously underwent treatment. Mick Bhatia, a professor in the department of Biochemistry and Biomedical Sciences,...
Cancer breakthrough uses CRISPR to target extra chromosomes
By Michael Irving - New Atlas Yale scientists have discovered a new potential treatment avenue to fight cancer. Using CRISPR gene-editing, the team eliminated extra chromosomes from cancer cells and found that they could no longer grow out of control. Healthy human...
17-Year-Old Who Beat Life-Threatening Disease Now Hopes to Become Doctor
By Anna Lazarus Caplan - People It was just after his eighth birthday when Hanif Mouehla found himself fighting for his life after being diagnosed with sickle cell disease. Inspired by the care he received, the 17-year-old is now eyeing the pre-med track at Harvard...
FDA approves world’s first cellular therapy for type-1 diabetes
by Mrigakshi Dixit - Interesting Engineering Named Lantidra, it's a cellular therapy developed using deceased donor pancreatic cells for the treatment of type 1 diabetes in adults. Therapy suitable for patients with hypoglycemia Type 1 diabetes makes the pancreas...
The new strategy may enable engineered T cells to eradicate solid tumors such as glioblastoma
By Anne Trafton | MIT News Office Engineering T cells to destroy cancer cells has shown success in treating some types of cancer, such as leukemia and lymphoma. However, it hasn’t worked as well for solid tumors. One reason for this lack of success is that the T cells...
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