News and Opinions
Researchers label early CAR-T therapy patient ‘cured’ after living a decade without cancer
By Angus Chen - Link to Article In 2010, Doug Olson became the second person in the world to receive CAR-T cell therapy, an experimental tactic to engineer his own immune cells to fight cancer. His doctors had tempered expectations for how well it would fight off...
ViaCyte and CRISPR Introduce New Stem Cell Therapy for Type 1 Diabetes
By Andrew Briskin - Link to Article In a collaboration between ViaCyte and CRISPR Therapeutics, a new clinical trial is investigating a cell therapy that may eventually help millions with type 1 diabetes. Researchers have long sought a cell-based “cure” for type 1...
UC Davis becomes first in region to grow cancer-fighting CAR T cells
Genetically modified cancer-fighting cells are now developed on campus as part of a new cellular therapy program (SACRAMENTO) Alan Gaines did two tours in the Vietnam War as a Navy fighter pilot—so being brave isn’t new to him. At 77, he was diagnosed with an...
Texas Heart Institute studying how stem cells treat heart failure
HOUSTON - (link to article) - A huge advancement in treating heart disease could be on the horizon. Researchers at the Texas Heart Institute are studying a high-tech way to use stem cells to spare lives and protect patients from the #1 killer. Your heart is a powerful...
CRISPR-Cas enzyme-based diagnostics to detect SARS-CoV-2 infection
By Dr. Tomislav Meštrović, MD, Ph.D. - Dec 13 2021 - News-Medical.net (link to article) A recent review in the journal Life provided a detailed description of CRISPR-Cas-based diagnostic techniques to identify severe acute respiratory syndrome coronavirus 2...
New Poll Demonstrates Bipartisan Support for Therapies that Target Aging and Associated Research
January 20, 2022 – Washington, D.C. (link to article) – A new national poll of registered voters in the United States shows that the majority of respondents would utilize pharmaceutical intervention to target aspects of aging if the drugs or therapies were safe,...
Experimental mRNA HIV Vaccine Safe, Shows Promise in Animals
NIAID Scientists Developed Vaccine Platform Image Caption: Scanning electromicrograph of an HIV-infected H9 T cell. Credit: NIAID December 9, 2021 - (Link to article) - An experimental HIV vaccine based on mRNA—the same platform technology used in two highly effective...
Using fungal vaccine to train stem cells and enhance immune response to infections
Reviewed by Emily Henderson, B.Sc. - Dec 16 2021 - News-Medical.net (link to article) The research group Immunology of Fungal Infections at the University of Valencia (UV) has investigated a fungal vaccine with which to train stem cells and hematopoietic progenitors...
‘Blastoids’ made of stem cells offer a new way to study fertility
Image caption: Human stem cells can be used to create models called blastoids (one shown that has been chemically altered to fluoresce) for studying how early-stage embryos implant into the lining of the uterus. Models of early-stage embryos could be used to research...
Reimagining stem cell cultivation
By Susan Buckles MayoClinic.com (link to article) Mayo Clinic has discovered how to microencapsulate pluripotent stem cells to potentially make them easier and less expensive to process and more effective for fighting disease. This research by Alexander Revzin, Ph.D.,...
Stem Cells or PRP for Equine Tendon and Ligament Injuries?
By Alexandra Beckstett, The Horse Managing Editor, TheHorse.com (link to article) Indications for their use and how veterinarians choose between the two therapies. In recent years, there’s been tremendous interest in using regenerative therapies (or, more accurately,...
First-ever pig-to-human heart transplant offers hope for thousands in need of organs
By Karen Weintraub - January 10, 2022 - APNews.com (link to article) A Maryland man has lived for three days with a pig heart beating inside his chest. The surgery, at the University of Maryland Medical Center, marks the first time a gene-edited pig has been used as...
Bayer Strikes “Mammoth” CRISPR Deal to Bolster Cell and Gene Therapy
By Alex Keown - Jan 10, 2022 - biospace.com (link to article) Bayer and Mammoth Biosciences forged a strategic collaboration potentially valued at more than $1 billion. The partnership grants the Germany-based pharma giant access to Mammoth’s CRISPR technology to...
Pfizer Makes Foray Into CRISPR, Inking $1.35 Billion Deal With Beam Therapeutics
By: ALLISON GATLIN - Investors.com - 01/10/2022 (link to article) Pfizer (PFE) is entering the CRISPR space through a $1.35 billion deal with Beam Therapeutics (BEAM), the companies announced Monday. But Beam stock fell on the deal. Beam is using CRISPR technology to...
For everything there is a season
As 2021 draws to a close, we celebrate the first decade of STEM CELLS Translational Medicine (SCTM) with gratitude to our devoted editors, reviewers, authors, and of course, our global loyal readership … all of you are a vital part of this first decade's history....
Stem Cell Therapy Safe, Shows Potential to Slow Progression in Trial
by Margarida Maia, PhD Repeat injections of mesenchymal stem cells (MSCs) into the spinal canal were safe and well tolerated in patients with amyotrophic lateral sclerosis (ALS), and showed potential to significantly slow the rate of disease progression, a small Phase...
Type 1 Diabetes Trial Tests Insulin-Secreting Implants Derived from Stem Cells
For the first time, scientists have derived insulin-secreting pancreatic endoderm cells from human pluripotent stem cells (PSCs), grafted these cells into 26 patients with type 1 diabetes, and demonstrated insulin secretion. The ongoing multicenter clinical trial aims...
New potential drugs for muscle dystrophy found using stem cells
November 29, 2021 - Kyoto, Japan - (Link to Article) Muscular dystrophy describes a group of genetic diseases in which muscles progressively weaken and degenerate, with Duchenne muscular dystrophy (DMD) being the most common. There are no curative treatments for DMD,...
“World’s first” 3D printed immunized skin model enables cold plasma wound healing treatment for burns
The NOVOPLASM consortium has announced it is the “first in the world” to develop cold plasma technology for the treatment of infected burns and the wound healing of skin grafts. Regenerative medicine firm CTIBIOTECH, the French Armed Forces Biomedical Research...
Stem cell memories may drive wound repair, and also chronic disease
by Rockefeller University A trifling paper cut is a site of frenzied activity. Within it, a squad of epidermal stem cells briskly regenerate to patch up the wound. A closer inspection of this war-torn swath of epidermis will reveal that while some of the stem cells...
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