News and Opinions

By Cedars Sinai - In July, Nick Mondek, MD, drove his healthy 9-year-old son Stephen to Cedars-Sinai on an important mission: To donate stem cells that might cure Mondek’s deadly blood cancer. Stephen’s donation would give Mondek a brand-new immune system—and make...

by Drug Target Review - A new experimental stem cell therapy shows promise in repairing brain damage after ischemic strokes – potentially allowing for the development of future treatments that extend the recovery window. Strokes are a leading worldwide cause of death...

By Drug Target Review - CAR T therapies are saving lives, but toxicities such as CRS and ICANS remain a major barrier. What will it take to overcome them? Chimeric antigen receptor (CAR) T-cell therapy is changing lives for patients with hard-to-treat cancers. By...

By Stem Cells Translational Medicine - Background The objective of this study was to assess the long-term effectiveness and safety of implanting mesenchymal stem cells derived from umbilical cord tissue (UC-MSC) in patients diagnosed with retinitis pigmentosa (RP)....

By Ekaterina Pesheva - Harvard Medical School - New AI tool accurately identifies multiple drivers of disease in cells and predicts therapies that can restore cells to healthy function. In a move that could reshape drug discovery, researchers at Harvard Medical School...

By Wired Magazine - Swedish researchers have developed two types of 3D bioprinting technology to artificially generate skin containing blood vessels. It could be a breakthrough in the quest to regenerate damaged skin. When treating severe burns and trauma, skin...

By Technology Networks - Peking University scientists have developed a groundbreaking cancer therapy that could make life-saving treatment accessible to any patient, anywhere. A team led by Professor Wei Wensheng from Peking University, collaborating with the PLA...

By UC San Diego Today - Findings reveal space-induced genetic, mitochondrial and inflammatory stress in blood-forming stem cells, offering insight into aging and risk of disease during long-duration space travel. Researchers from University of California San Diego...

by Alejandra Manjarrez, PhD - Exploring Drug Discovery and Development = Macrophage-based therapies for liver cirrhosis are entering clinical trials, but key challenges remain before they become a viable treatment. Macrophages — key players of the immune system —...

By By Tiare Dunlap, University of California - SciTechDaily - Antidepressants help immune cells fight cancer. They may improve therapy effectiveness. A commonly prescribed antidepressant may also strengthen the body’s defenses against cancer, according to new research...

By Journal of Drug Delivery Science and Technology - Abstract Wound healing is the process of tissue regeneration, which, under normal conditions, is a very time-consuming process. It is also very susceptible to complications such as infection and chronic...

by University of Geneva - MedicalXpress - Transplanting hematopoietic stem cells from healthy individuals is one of the possible treatments for blood cancers. In Switzerland, it involves nearly 300 patients per year. However, nearly half of transplants fail, mainly...

By PESACH BENSON/TPS - The Jerusalem Post - Tel Aviv University announced on Wednesday that the surgery will take place in Israel, marking a historic milestone in regenerative medicine. Israel is preparing to perform the world’s first-ever human spinal cord implant...

By By Erin Digitale, Stanford Medicine - SciTechDaily - A Phase 1 clinical trial has shown that an antibody developed at Stanford Medicine can prepare patients for stem cell transplantation while avoiding toxic side effects. A phase 1 clinical trial has demonstrated...

By The University of Osaka - Science Daily - Researchers from The University of Osaka develop time-deterministic cryo-optical microscopy, which freezes cells with millisecond precision, enabling accurate, high-resolution visualization of transient moments during...

by University of Chicago Medical Center - MedicalXpress - Researchers at the University of Chicago have developed a "universal" chimeric antigen receptor (CAR) platform that offers enhanced safety, adaptability, and the potential to overcome long-standing barriers in...

by Andrea Lius, PhD - The Scientist - Researchers bank on stem cells to study developmental biology, understand oral cancer, regenerate organs, and save species on the brink of extinction. Stem cells can self-renew and differentiate into a wide variety of cell types,...

by Quentin Johnson - dvidshub.net - FORT DETRICK, Md.– Scientists at the U.S. Army Medical Research Institute of Infectious Diseases have successfully created a novel 3D bioprinted vascular liver tissue model, marking a significant advancement in biomedical research...

By Penn Medicine - The ability of a newly understood stem cell originating in skeletal muscle to turn into bone could hold the key to bone healing after catastrophic fractures. When bones break and there is extreme tissue loss—such as after a car accident or a...

by Michael Gibney - PharmaVoice - The first cell therapy approved by the FDA, Dendreon’s Provenge for prostate cancer, had a bumpy start on the market in 2010, as the autologous treatment was logistically difficult to manufacture and administer, and thus also to...