News and Opinions
Scientists Partially Revived Pig Organs An Hour After Death In ‘Stunning’ New Research
Here's a headline you don't see every day. Stunning- #organs revived after death! Could this one day be an answer to organ shortages? Or a plot straight out of a dystopian TV show on the SyFy Channel. Article in #Forbes provides the quick takeaway: "The research works...
Ageing and rejuvenation of tissue stem cells and their niches
Abstract Most adult organs contain regenerative stem cells, often organized in specific niches. Stem cell function is critical for tissue homeostasis and repair upon injury, and it is dependent on interactions with the niche. During ageing, stem cells decline in their...
An abundance of CAR-Ts: $37B cell therapy cancer market can’t support ‘congested’ pipeline, report says
Image caption: Market over-saturation is especially pronounced in acute lymphocytic leukemia, which has more than 300 drugs in the pipeline, plus two that boast FDA approvals, GlobalData points out. (Mohammed Haneefa Nizamudeen/iStock/Getty Images Plus) By Fraiser...
Pediatric Urologist Dr. Anthony Atala to Receive 2022 Jacobson Innovation Award
Dr. Atala leads an interdisciplinary team that has developed 15 clinically used tissue applications and is working on more than 40 tissues and organs Newswise — CHICAGO (June 10, 2022): Anthony Atala, MD, FACS, Winston-Salem, North Carolina, will be presented with the...
New stem cell models for aging and eye diseases
Seeing a brighter future! Highly interesting article. Using stem modeling with #IPSCs, researchers at the #UniversityofMelbourne developed genetic roadmaps for two causes of irreversible #blindness - Primary Open-Angle Glaucoma #POAG and age-related macular...
A Blueprint for Turning Stem Cells Into Sensory Interneurons
image Caption: Sensory interneurons (with nuclei in red) derived from mouse stem cells. Credit: UCLA Broad Stem Cell Research Center Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a...
Reactivating Type 1 diabetics’ pancreatic stem cells to produce insulin
image caption: Microscope image of pancreatic tissue, magnification 25X. Shows Islets of Langerhans (lightly stained, pink areas - composed of alpha and beta cells, endocrine tissue), and exocrine tissue (darker, surrounding tissue, secretes digestive enzymes)....
Stem Cells Used to Repair Heart Defects in Children
Doctors turn to stem cell treatment to heal the youngest hearts Almost one out of 100 babies are born with a heart defect each year in the United States. Many of these babies will need surgery within weeks of birth, followed by more surgeries throughout their lives....
The chemical controlling life and death in hair follicles
Image Caption: New research into factors that control the life and death of hair follicle cells could help people with baldness, as well as wound healing. Credit: Helpaeatcontu/Wikimedia by Jules Bernstein, University of California - Riverside A single chemical is key...
Charles River jumps into cell and gene therapy manufacturing with $875M Cognate buy
By Fraiser Kansteiner - Fierce Pharma Just a few weeks after Cognate BioServices moved to beef up its cell and gene therapy manufacturing, the company has attracted a buyer eager to tap that expertise. Charles River Laboratories agreed to throw down $875 million cash...
Vertex absorbs ViaCyte and its stem cell-based diabetes treatment for $320M, clearing out competition
By Max Bayer - Fierce Biotech Just a week after Vertex’s stem cell therapy to treat type 1 diabetes was released from an FDA clinical hold, the company is clearing out potential competition by buying ViaCyte for $320 million. The all-cash deal announced Monday throws...
A major step forward for organ biofabrication
By recreating the helical structure of heart muscles, researchers improve understanding of how the heart beats By Leah Burrows - Harvard John A Paulson School of Engineering and Applied Sciences Heart disease — the leading cause of death in the U.S. — is so deadly in...
A Newly Discovered Type of Stem Cell Could Allow Scientists To Make Organs in a Dish
By University of Copenhagen - SciTechDaily.com The University of Copenhagen researchers utilized a mouse model to discover an alternate path that some cells follow to build organs and used that information to exploit a new kind of stem cells as a possible supply of...
New study allows researchers to more efficiently form human heart cells from stem cells
By Rebekah McBride - University of Wisconsin–Madison Lab-grown human heart cells provide a powerful tool to understand and potentially treat heart disease. However, the methods to produce human heart cells from pluripotent stem cells are not optimal. Fortunately, a...
Mayo Clinic – Bringing Regenerative Technology of the Future to Patients Today
By Susan Buckles "The sky's the limit," "possibility" and "potential cure for disease" are aspirational ways Mayo Clinic physicians and scientists described regenerative medicine in a recent virtual presentation at the World Stem Cell Summit 2022. Mayo's panel...
UPDATE: Convicted Italian Surgeon Gets Sentence Appealed in High-Profile Case
Swedish prosecutors have appealed a sentence given to an Italian surgeon who was prosecuted for causing bodily harm during experimental stem-cell windpipe transplants By AP COPENHAGEN, Denmark (AP) - Swedish prosecutors on Wednesday appealed a sentence given to an...
Scientists Find A Multidimensional Universe Inside the Human Brain
"Algebra, much less "algebraic topology", was never my strong suit. However, reading this fascinating article definitely stimulated the 11 dimensions in my aging lawyer's brain! According to a study published in "Frontiers in Computational Neuroscience", the...
Hair Loss Treatment Uses Stem Cells to Generate Healthy New Follicles
By Gail Dutton - Genetic Engineering and Biotechnology News Stemson Therapeutics is harvesting patient cells, generating and differentiating iPSCs, and pro-ducing dermal papilla cells in abundance Hair loss can be distressing, even devastating, but it isn’t considered...
Scientists grow cells on a robot skeleton (but don’t know what to do with them yet)
A new method of tissue engineering is only a proof of concept for now By James Vincent - The Verge The science of tissue engineering — or growing human cells for use in medicine — is very much in its infancy, with only the simplest lab-grown cells able to be used in...
Penn Medicine Developed CAR T Cell Therapy Wins Third FDA Approval
PHILADELPHIA – The U.S. Food and Drug Administration (FDA) has expanded its approval for a personalized cellular therapy developed at the University of Pennsylvania’s Abramson Cancer Center, this time for the treatment of adults with relapsed or refractory follicular...
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