News and Opinions
A research partnership brings gene editing promise to eye disease
by Brian Mattmiller In order to tap the tremendous potential of CRISPR gene editing technology for reversing human disease, Wisconsin scientists are working with a star pupil. The human eye — though one of the body’s most complex and intricate structures — happens to...
Could Stem-Cell Based Therapy Treat Type-1 Diabetes? A New Study Demonstrates the Treatment’s Potential
By The Endocrine Society The findings suggest stem cell-based replacement therapy has the potential to manage blood sugar levels and may eventually replace the requirement for external insulin injections or dosing. Stem-cell therapy has promise in the treatment of...
Pioneering stem-cell trials in Japan report promising early results
The country has invested hundreds of millions of dollars into research on induced pluripotent stem cells to treat diseased organs. by: Smriti Mallapaty - Nature Some of the first trials to test whether reprogrammed stem cells can repair diseased organs have begun to...
Moderna sues Pfizer, BioNTech over COVID-19 vaccine
Moderna is suing Pfizer and BioNTech, alleging they copied technology that Moderna first developed years before the pandemic in producing the first COVID-19 vaccine approved in the U.S., the company announced Friday. Driving the news: Moderna is seeking unspecified...
‘Synthetic’ embryo with brain and beating heart grown from stem cells by Cambridge scientists
By Sarah Collins and Jacqueline Garget - University of Cambridge Researchers from the University of Cambridge have created model embryos from mouse stem cells that form a brain, a beating heart, and the foundations of all the other organs of the body – a new avenue...
Hydrogel that outperforms cartilage could be in human knees in 2023
By Michael Irving - New Atlas Joint pain is a common ailment of aging, thanks to cartilage’s tendency to wear out. Now, researchers at Duke University have developed a new hydrogel that’s stronger and more durable than the real thing, which could make for longer...
Personalized Immunotherapy Shows Promise Beyond Cancer
AUDIO -Science Friday Article CAR T cell therapy, a type of immunotherapy in which a patient’s own immune cells are modified to create a hybrid immune cell that destroys cancer cells, was first developed over a decade ago. Now, researchers are continuing to...
The New York Stem Cell Foundation Mourns the Loss of CEO Susan L. Solomon
One of the great patient advocates of our time, Susan Solomon, has passed away. Susan was a visionary leader and true force of nature. A diabetes mom, she launched the New York Stem Cell Foundation that has supported cutting edge research and constructed a major...
Large number of stem cell lines carry significant DNA damage, say researchers
DNA damage caused by factors such as ultraviolet radiation affect nearly three-quarters of all stem cell lines derived from human skin cells, say Cambridge researchers, who argue that whole genome sequencing is essential for confirming if cell lines are usable. Stem...
Creating an “Adult-like” Mature Human Cardiac Tissue
Model developed by UConn and UCSF researchers to be used for myriad of applications, most notably to evaluate safety and efficacy of drugs on the cardiovascular system By Courtney Chandler - UConn Health Researchers in the Biomedical Engineering Department at UConn...
MIT researchers develop test that measures COVID-19 immunity
"Our test’s accuracy was roughly about as accurate as you would see for a normal blood test." By Madeleine Aitken Researchers at MIT have developed a test that measures immune protection against COVID-19 by measuring the level of neutralizing antibodies in a blood...
First U.S. patient receives autologous stem cell therapy to treat dry AMD
Breaking News in #maculardegeneration! First time in USA! Commencement of a Phase 1/2a clinical safety trial using #IPSC stem cells to treat for advanced dry age-related macular degeneration. NIH and #JohnHopkins surgical team implanted a patch of tissue made from...
Bringing regenerative technology of the future to patients today
By Susan Buckles - Mayo Clinic "The sky's the limit," "possibility" and "potential cure for disease" are aspirational ways Mayo Clinic physicians and scientists described regenerative medicine in a recent virtual presentation at the World Stem Cell Summit 2022. Mayo's...
CRISPR Gene Editing Critical to Delivering Off-the-Shelf Cell Therapy
By Vivienne Raper, PhD - Genengnews.com The future of cell therapies should be in off-the-shelf products using multiplex gene editing during the manufacturing process. That’s according to Rachel Haurwitz, PhD, CEO of Caribou Biosciences. Haurwitz, whose colleague...
New inhaled COVID-19 therapeutic blocks viral replication in the lungs
By Kara Manke - Berkley News UC Berkeley postdoctoral scholar Chi Zhu is part of a team of researchers who are developing a new COVID-19 therapeutic that can be administered as a nasal spray. The experimental treatment is effective against all SARS-CoV-2 “variants of...
A New Approach to T-Cell Therapy
By Katie Brighton - Technology Networks T-cell therapy is a growing field, with applications moving beyond treating blood cancers to treating solid tumors too. Progress is also being made towards using T-cell therapy to treat infectious diseases such as human...
Time’s Arrow – Brief exposure to rapamycin has the same anti-ageing effects as lifelong treatment
Just published! Some are hailing this promising discovery the next Fountain of Youth, but let's not get carried away. Brief exposure to drug #rapamycin has the same anti-aging effects as lifelong treatment. The #MaxPlanckInstitute made headlines in the #longevity and...
Pioneering stem-cell trials in Japan report promising early results
Has public enthusiasm for #IPSCs waned in Japan? The subject article addresses the topic by focusing on three ongoing studies. Transplanting reprogrammed heart muscle stem cells into a patient. Transplanting IPSC derived #cornea cells- with some vision improvement...
Mystery cells that create blood stem cells in mammals identified
by University of New South Wales - Phys.org Imagine if one day blood transfusions from strangers were not needed because they could be produced from cells that line your own blood vessels' cells. While that day is still some years off, medical researchers at UNSW...
Regenerative medicine is now ready to drive longevity forward
Regenerative Medicine Foundation director highlights the need for patient advocacy in longevity and calls for treatments to be made available to all – not just the few. Author: Danny Sullivan - Link to Article Regenerative medicine is one of the most promising areas...
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