News and Opinions
Exploring mesenchymal stem cells homing mechanisms and improvement strategies
By Stem Cells Translational Medicine - Mesenchymal stem cells (MSCs) hold tremendous potential for regenerative medicine and the treatment of currently incurable diseases. These adult multipotent progenitor cells are essential for tissue regeneration and wound repair...
Largest ALS patient-based stem cell, biodata resource opens for research
by Lindsey Shapiro, PhD - ALS News Today - Answer ALS and Cedars-Sinai have made openly available their amyotrophic lateral sclerosis (ALS) patient-based stem cell and biodata repository to researchers worldwide. The largest of its kind, the repository contains...
A sliver of lab-grown wood has been made from stem cells
By James Dinneen - New Scientist - Growing wood directly from stem cells could offer an alternative to cutting threatened hardwood trees, but it isn't clear if it has same properties as actual wood. What may be the world’s first piece of lab-grown wood isn’t quite big...
Novel CAR T-cell therapy demonstrates efficacy and safety in preclinical models of HER2-positive solid tumors
By VHIO - One-third of HER2-positive (HER2+) tumors express the P95HER2 protein, which associates with an aggressive form of breast cancer with a poorer prognosis. Investigators of the VHIO’s Growth Factors Group, and the Cancer Research Program of Hospital del Mar...
3D-printed regenerative blood products boost healing
By The Engineer - Engineers at Nottingham University have 3D-printed blood-based regenerative materials that mimic natural healing processes and enhance recovery. Described in Advanced Materials, the ‘biocooperative’ materials combine a subject’s own blood with...
CAR T-Cell Therapy Shows Efficacy in Young Patients with Incurable Brain Cancer
By Genetic Engineering and Biotechnology News Clinical trial results are showing the first successes against solid tumors for CAR-T cells. The findings offer hope for children with a group of deadly brain and spinal cord tumors, including a cancer called diffuse...
Boost aging patients’ meaningful access to health tech
By Andis Robeznieks - American Medical Association - It is critically important to make health IT accessible for all and to achieve equitable adoption among aging patients, people with hearing and eyesight impairment, as well as those who live in communities...
The First Crispr Treatment Is Making Its Way to Patients
by Emily Mullin - Wired - It’s been a year since the gene-editing treatment Casgevy was approved for sickle cell disease and a related blood disorder. It’s finally being infused into patients. Called Casgevy, the gene-editing treatment is for people with sickle cell...
Scientists recreate mouse from gene older than animal life
by Queen Mary University of London News New research sheds light on evolutionary origins of stem cells with groundbreaking experiment to create mouse using ancient genetic tools Published in Nature Communications, an international team of researchers has achieved an...
Netrin1 Protein Plays a Critical Role in Spinal Cord Development
By The Broad Stem Cell Research Center - Technology Networks - Researchers have uncovered an unexpected role for the molecule netrin1 in organizing the developing spinal cord. Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell...
Markers in iPSC quality control—a new approach to enhance standardization
by Christiane Klasen - Phys.org - Human induced pluripotent stem cells (iPSCs) have a great potential for scientific and medical applications. They are used in research laboratories to model human diseases, helping to uncover underlying mechanisms and developing new...
World-first stem-cell treatment restores vision in people
By Smriti Mallapaty - Nature - The treatment, given to four people with damaged corneas, seems safe but needs to be tested in larger trials. Three people with severely impaired vision who received stem-cell transplants have experienced substantial improvements in...
‘Serial Killing’ Cell Therapy From Autolus Lands FDA Approval in Blood Cancer
By Frank Vinluan - MedCity News - Autolus Therapeutics’ Aucatzyl is now FDA approved for treating advanced cases of B-cell precursor acute lymphoblastic leukemia. While it goes after the same target as Gilead Sciences’ Tecartus, Autolus engineered its CAR T-therapy...
Mini-lungs could help fight flu & colds by tapping immunity
by Imma Perfetto - Cosmos - An Australian researcher has been awarded $60,000 to build more complex models of the human lung, with the hope to discover new therapies for respiratory diseases. Dr Rhiannon Werder, team leader at the Murdoch Children’s Research Institute...
Human stem cell-derived heart cells are safe in monkeys, could treat congenital heart disease
By By Jordana Lenon - University of Wisconsin-Madison - Heart muscle cells grown from stem cells show promise in monkeys with a heart problem that typically results from a heart defect sometimes present at birth in humans, according to new research from the University...
Nasal Spray Made From Stem Cell-Derived Vesicles Could Treat Alzheimer’s Disease
By Texas A&M College of Medicine News - A new therapy may delay Alzheimer’s disease progression by years, according to a study by researchers at Texas A&M University College of Medicine. Published in the Journal of Extracellular Vesicles, the research aims to...
New Stem Cell Data From Space
Arun Sharma, PhD By Cedars Sinai News - Cedars-Sinai investigators are one step closer to manufacturing stem cells in space, which could speed up the development of new medical therapies on Earth. The first published data from the experiments conducted on a private...
Stem cell therapy improves mental, physical health in relapsing-remitting MS
By Healio News - Top-line results of a phase 2 clinical trial for an adipose-derived autologous mesenchymal stem cell therapy to address mild to moderate relapsing-remitting MS found the treatment improved mental and physical health at 52 weeks. According to a press...
UNH Awarded $10M to Support Workforce Development in ReGen Valley Tech Hub Initiative
By UNH Manchester - The University of New Hampshire at Manchester has been awarded $10 million to lead workforce development efforts within the ReGen Valley Tech Hub, an initiative aimed at establishing Southern New Hampshire as a global leader in biofabrication....
Gene Editing Insights Progress Delivery Inside Body
By Inside Precision Medicine - U.S. researchers have shone further light into the precise way that CRISPR/Cas9 gene editing actually works and circumvents unintended off-target effects, which could lead to more accurate cellular therapies. The preclinical research,...
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