News and Opinions
Tailoring cell therapies for diabetic metabolic phenotypes: a comparative study on the efficacy of various umbilical cord-derived cell regimens
By Stem Cells Translational Medicine Given the high heterogeneity of type 2 diabetes mellitus (T2DM), it is imperative to develop personalized stem cell infusion regimen for targeted metabolic phenotype in order to ensure optimal therapeutic efficacy. In this study,...
New study shows stem cell therapy ‘jump-start’ brain repair after stroke
by Gladstone Institutes - MedicalXpress - Every 40 seconds, someone in the United States has a stroke. For survivors of the most common type of stroke, called an ischemic stroke, only about 5 percent fully recover. Most others suffer from long-term problems, including...
Enhanced bone regeneration using mesenchymal stem cell-loaded 3D-printed alginate-calcium Titanate scaffolds: A Calvarial defect model study
By Science Direct - This study investigates the efficacy of a 3D-printed alginate composite scaffold enriched with calcium titanate nano powders and loaded with mesenchymal stem cells (MSCs) for bone regeneration in a calvarial defect model. Scaffolds (20 mm × 20 mm ×...
Penn researchers develop temperature-sensitive protein with applications in cancer cell therapy
By Megan Liu - The Daily Pennsylvanian - A group of Penn scientists has developed a new method to remotely control engineered cells inside the human body using heat. Led by bioengineer Lukasz Bugaj, the innovation introduces a temperature-sensitive protein called...
Korea permits stem cell therapies for arthritis, autoimmune diseases, and Parkinson’s patients
By Heo Ji-yoon - Chosun Biz - Korean patients gain access to innovative regenerative medical treatments after law changes. Next month, patients with severe, rare, and incurable diseases such as arthritis, autoimmune diseases, Parkinson's disease, and cancer will be...
New study shows stem cell therapy ‘jump-start’ brain repair after stroke
by Gladstone Institutes - MedicalXpress - Every 40 seconds, someone in the United States has a stroke. For survivors of the most common type of stroke, called an ischemic stroke, only about 5 percent fully recover. Most others suffer from long-term problems, including...
‘Fatty cartilage’ discovery set to revolutionize regenerative medicine
By Paul McClure - New Atlas - Researchers have discovered a new type of tissue, a soft and flexible ‘fatty cartilage’ that could revolutionize the treatment of traumatic injuries, birth defects, and cartilage-damaging diseases like osteoarthritis, rheumatoid arthritis...
UCLA scientists awarded $21.8 million in CIRM grants to advance novel stem-cell based therapies
by Linda Wang - UCLA Health - Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received $21.8 million in grants from the California Institute for Regenerative Medicine, the state’s stem cell agency, to develop...
Autologous Implants: The New Hope for Spinal Cord Injury Treatment
By Asaf Levon - Haaretz News - Can damaged parts of the spinal cord be replaced with functional nerve tissues? Matricelf aims to make this vision a reality with groundbreaking technology. In the company's laboratories in Nes Ziona, a team of about ten experts in...
Healthspan Compass – Vol. 9 – from Healthspan Action Coalition
By Eve Herold - Healthspan Action Coalition - Before we launch into news on the healthspan front, let’s acknowledge the elephant in the room. US health agencies, including the National Institutes of Health and the FDA, are currently in a state of limbo as the dust...
The compassionate team behind CAR T cancer breakthroughs
By: Nicole Sweeney Etter - Penn Medicine News - For more than a decade, Penn Medicine clinical research nurse Joanne Shea, MS, BSN, RN, has had a front-row seat to the groundbreaking research underway in the Center for Cellular Immunotherapies. As Abramson Cancer...
Youthful Brain Stem Cells Linked to Autism and Brain Cancer
By Neuroscience News - Researchers have identified a unique stem cell in the young brain capable of maturing into multiple cell types, potentially explaining the origins of autism and glioblastoma. These stem cells show gene expression patterns that regulate early...
JPM25: Bayer moves allogeneic cell therapy into phase 3 Parkinson’s trial
By Gabrielle Masson - Fierce Biotech - Bayer’s Parkinson’s disease cell therapy is moving into late-stage testing, with the upcoming trial set to be the first registrational phase 3 study for an investigational allogeneic cell therapy in the neurodegenerative disease....
10 Mayo Clinic research advances in 2024, spanning stem cell therapy in space to growing mini-organs
By Mayo Clinic - ROCHESTER, Minn. — At Mayo Clinic, researchers published more than 10,000 scientific papers in 2024 that are driving medical discoveries, leading to new cures for the future. The following are 10 research highlights from Mayo Clinic this year: Growing...
Princeton bioengineers shed light on how and when embryonic cells organize themselves
By Wright Seneres - Princeton Engineering - For decades, scientists have puzzled over how a symmetrical ball of cells becomes an embryo, with the beginnings of a head and tail. Now Princeton engineers have discovered that this transformation from perfect symmetry to...
The Download: what’s next for AI, and stem-cell therapies
By By Rhiannon Williams - MIT Technology Review - Stem-cell therapies that work: 10 Breakthrough Technologies 2025 A quarter-century ago, researchers isolated powerful stem cells from embryos created through in vitro fertilization. These cells, theoretically able to...
Automated iPS cell production to start in Japan in April
By Jiji - The japan Times - Kyoto – Following its success in automating the process of creating induced pluripotent stem cells, Kyoto University's CiRA Foundation will start producing iPS cells from patients' own cells utilizing the automated culture system in April....
Correcting Genetic Spelling Errors With Next-Generation Crispr
By Francis Collins for Wired - Treatments for rare diseases are hard to create and expensive to deliver, but there is new hope for editing the software of the genome. Sam Berns was my friend. With the wisdom of a sage, he inspired me and many others about how to make...
It was so easy to give people more years of life with my Stem Cells
by Storm Newton - BBC - A man has given his stem cells twice in the space of a decade to help save the lives of two people. Brad Green, from Sheffield, was inspired to sign the Anthony Nolan stem cell register at the age of 20 after a school friend's dad was diagnosed...
Brain tumor organoids accurately model patient response to CAR T cell therapy
by Penn Medicine News - Lab-grown tumors respond to cell therapy the same as tumors in the patients’ brains, according to Penn researchers PHILADELPHIA— For the first time, researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM)...
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