News and Opinions
Human skin map gives ‘recipe’ to build skin and could help prevent scarring
by Wellcome Trust Sanger Institute - MedicalXpress - For the first time, researchers have created a single cell atlas of prenatal human skin to understand how skin forms, and what goes wrong in disease. Researchers from the Wellcome Sanger Institute, Newcastle...
Comparative analysis of single versus tandem autologous stem cell transplantation in patients with multiple myeloma in Korea: the KMM2102 study
By - Nature - Despite treatment advances, multiple myeloma (MM) remains incurable1. High-dose chemotherapy followed by autologous stem cell transplantation (ASCT) is considered the standard treatment for eligible patients2,3. Moreover, ASCT is reportedly effective and...
A new era of COVID-19 brings new outlooks for cellular therapy recipients
By A Donlan - Fred Hutch Cancer Center - During the COVID-19 pandemic, it quickly became clear that certain populations were particularly at risk for severe disease. Individuals undergoing hematopoietic cell transplants (HCT) or chimeric antigen receptor T-cell (CART)...
Researchers identify gene crucial to blood stem cell regulation, growth
By Danielle H. Cho - Daily Bruin - UCLA researchers have found a gene that may have implications for treating blood-related genetic diseases and cancers. All types of blood cells come from blood stem cells, said Júlia Aguadé-Gorgorió, the first author of the paper...
Scientists Use CRISPR Tools to Safely Disable Gene Mutation Linked to Advanced Skin Cancer
By Christiana Care News - In a potential advance for melanoma patients, researchers at ChristianaCare’s Gene Editing Institute have used CRISPR gene editing tools to disable a gene mutation often seen in aggressive forms of this dangerous skin cancer that renders...
Scientists Use Human Stem Cells to Restore a Monkey’s Vision
by Maggie Harrison Dupré - Neoscope - Scientists have successfully used human stem cells to patch a hole in a monkey's retina, restoring the primate's vision and marking a successful step forward in the quest to treat age-related vision loss. As detailed in a study...
Cell and gene therapy approvals drive paradigm change in manufacturing
by Irena Maragkou - Pharmaceutical Technology - Innovative cell and gene therapies (CGTs) have significantly disrupted the treatment landscape for several genetic diseases. In recent years, the number of CGT approvals has been on an upward trajectory, with there being...
CAR T-Cell Therapy: Pathology Is Key to This Revolutionary Cancer Treatment
by Isabella Backman - Yale School of Medicine - CAR T-cell therapy, officially known as chimeric antigen receptor (CAR) T-cell therapy, is among the newest cancer treatments that harness our immune system— the powerful network of cells, tissues, and organs that fights...
World’s first ovarian cancer vaccine being developed in UK ‘could wipe out the disease’
By Sky News - The world's first ovarian cancer vaccine could wipe the disease out, researchers have said. OvarianVax is a vaccine that teaches the immune system to recognise and attack the earliest stages of ovarian cancer. It's being developed by scientists at the...
Purdue and UPenn research finds link between aging, fat accumulation in the brain
By Purdue University - With age, some cells in the brain enter a state of senescence: rather than dying or regenerating by dividing, they just linger, alive, but functioning less effectively than normal cells. Senescence in the brain has been linked to cognitive...
Selling ‘snake oil’? The days are numbered for stem cell clinics
By Alexis Rivas - NBC Channel 7 News, San Diego CA - A federal appeals court handed the FDA power to shut down unproven stem cell treatments The future of stem cell clinics across San Diego County, California, and the country are at risk. A federal appeals court in...
“Functional cure” for diabetes restores insulin production with stem cells
By Michael Irving - New Atlas - A patient with type 1 diabetes has been functionally cured of the disease, requiring no insulin doses for over a year. The treatment involves growing and transplanting new insulin-producing cells from the patient’s own stem cells. Type...
Researchers Now Know How Killifish Regenerate Their Fins
By Technology Networks - The researchers say their findings could inform regenerative medicine in humans. Spontaneous injuries like the loss of a limb or damage to the spinal cord are impossible for humans to repair. Yet, some animals have an extraordinary capacity to...
Stem cells reverse woman’s diabetes — a world first
By Smriti Mallapaty - Nature - A 25-year-old woman with type 1 diabetes started producing her own insulin less than three months after receiving a transplant of reprogrammed stem cells1. She is the first person with the disease to be treated using cells that were...
Ninth Circuit strengthens FDA authority to enforce drug regs against certain stem cell products
By Hogan Lovells – The U.S. Court of Appeals for the Ninth Circuit on Friday reversed the district court’s judgment in United States v. California Stem Cell Treatment Center, siding with the U.S. Food and Drug Administration (FDA) in finding that a stem cell clinic’s...
Healthspan Action Coalition Rally Celebrates International Longevity Day
San Francisco, CA, September 26, 2024—October first is worldwide International Longevity Day, and the Healthspan Action Coalition will mark the day with a public rally in the heart of San Francisco’s research and healthcare community. The event, which will be led by...
What T Cell Cancers Can Teach Us About T Cell Therapy
By Cancer Health - Adoptive T cell therapies, in which a patient’s own immune cells are genetically engineered to target their cancer cells, have been remarkably effective in treating certain blood cancers. Unfortunately, this success has not translated to solid...
Study discovers new process for cells to repair DNA damage
By University of Oxford - A team of international researchers at the University of Oxford (Oxford) and Nanyang Technological University, Singapore (NTU Singapore), has discovered a new process for repairing damaged DNA that is particularly relevant for patients...
Damaged small intestine repaired with hPSC-derived organoids
By Drug Target Review - Cincinnati Children’s have made a significant achievement in organoid medicine, with their new study detailing how lab-grown human tissue successfully repaired damaged intestines in a rodent model. This moves decades of research efforts closer...
Scientists advance type 1 diabetes treatment with cutting-edge stem cell and gene editing technologies
By Dr. Sushama R. Chaphalkar, PhD. - NewsMedical.net - Unlocking the potential of renewable β cells and precision gene editing, researchers aim to revolutionize diabetes care and bring us closer to a functional cure for type 1 diabetes. In a recent study published in...
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