News and Opinions
Shared Facility Spotlight: Pluripotent Stem Cell Facility
By CincinnatiChildrens.org - Cincinnati Children’s Pluripotent Stem Cell Facility (PSCF) facilitates and supports research using human pluripotent stem cells (hPSCs). HPSCs are generated from a skin biopsy or blood sample that can be obtained from any patient and,...
Engineered stem cells target autoimmune diseases
By Adam Boros, PhD - Drug Discovery News - Genetically modified stem cells show promise in a targeted approach to taming inflammation in autoimmune diseases. Researchers developed an immunotherapy using chimeric antigen receptors and mesenchymal stromal cells, paving...
BioXtek: Creating cutting-edge regenerative therapeutics from human birth tissue
by Phil Newman - Longevity.Technology - At birth, the baby is the headline event while the rest of the materials, which have played a crucial role in the intricate process of building a fully-functioning human from just two cells, are often discarded as medical waste....
Scientists create a cell that precludes malignant growth
By University of Helsinki - Phys.org - Cell therapies could help in the treatment of hereditary diseases, myocardial infarction and hundreds of other diseases. For many blood diseases, new cells can already be transplanted into human patients, and diabetes has also...
A patch fitted with stem cells helps repair damaged spinal cords
by Clara Rodriguez Fernandez - Advanced Science News - Scientists have taken a step closer toward a treatment to repair damaged spinal cord tissue with a wireless patch that delivers electrical pulses to stem cells. The device could overcome some major hurdles in the...
Prime Editing Corrects Cystic Fibrosis Mutation
by Gorm Pamgren - CRISPR Medicine News - Researchers have refined prime editing (PE) to correct the cystic fibrosis (CF) related gene CFTR. Results demonstrated improved efficiency and minimal off-target effects in correcting the F508del mutation in human airway...
Trial of cell-based therapy for high-risk lymphoma leads to FDA breakthrough designation
By Science Daily News - CAR-T cell therapy helps some with intractable lymphoma, but those who relapse have few options. Modifying the therapy's molecular target improved response. Source: Stanford Medicine. Click Here to read the article
CAR T cell therapy for pediatric brain cancer warrants further study
By Baylor College of Medicine - Novel therapeutic approaches are needed for children with diffuse midline glioma (DMG) and other recurrent high-grade central nervous system (CNS) tumors, aggressive brain cancers with poor prognoses. A type of immunotherapy using T...
J.P. Morgan’s private financing arm closes inaugural $500M-plus biotech fund
By Gabrielle Masson - Fierce Biothech - J.P. Morgan Private Capital has closed an inaugural life sciences fund of more than $500 million, cash that will go toward a wide range of private biotechs and build value for existing portfolio companies. Dubbed the “270 Life...
Eyesight from a 3D Printer
By Karlsruhe Institute of Technology - KIT Researchers and Industry Partners Develop Process for Printing Personalized Corneas; Project Wins NEULAND Innovation Contest Printing a new cornea during an operation to restore a patient’s eyesight: This groundbreaking step...
Growth factors linked to stem cell aging in bone marrow study
by Jackson Laboratory - Medical Express - Our bone marrow—the fatty, jelly-like substance inside our bones—is an unseen powerhouse quietly producing 500 billion new blood cells every day. That process is driven by hematopoietic stem cells that generate all of the...
Stem cell therapy for interstitial cystitis/bladder pain syndrome
By PubMed - The analysis on phase 1/2a trial which had several modifications in protocol is currently ongoing. Despite several limitations that need to be overcome, stem cell therapy could be a potential therapeutic option for treating IC/BPS. Clinical outcome on...
Stem Cell Therapy Development Embraces New Technologies
By Genetic Engineering and Biotechnology News - Stem cell research recently celebrated its 60th anniversary. Although the first publications in this field appeared in the early 1960s, it took another 20 years before the first embryonic stem cells could be isolated....
Fertility treatments could get a boost from stem cells
by University of Copenhagen - MedicalXpress - An unexpectedly versatile and regenerative stem cell in early embryos may be key to creating new effective fertility treatments, suggests a new study in mice from the University of Copenhagen. The paper, titled "The...
Huntington Disease Gene Therapy Nets RMAT Designation
By Victoria Johnson - CGT Live = The FDA has granted Regenerative Medicine Advanced Therapeutic (RMAT) Designation to uniQure’s AMT-130 gene therapy for the potential treatment of Huntington disease (HD).1 “We’re thrilled to receive the first ever RMAT designation for...
Lab-grown muscles reveal mysteries of rare muscle diseases
By Duke University - Science Daily - Biomedical engineers at Duke University have developed a new technique to better understand and test treatments for a group of extremely rare muscle disorders called dysferlinopathy or limb girdle muscular dystrophies 2B (LGMD2B)....
Stem Cell Plasticity: A Double-Edged Sword
by Hannah Thomasy, PhD - The Scientist - Yejing Ge explores the behavior of skin-resident stem cells in wound repair, cancer, and aging. In 1986, Harold Dvorak, a pathologist at Harvard Medical School, popularized the idea of cancer as a wound that does not heal. In...
Unraveling the Mysteries of Stem Cells
By Gret Harrison - USC Viterbi - New research harnesses machine learning and imaging to give unprecedented insight into stem cell behavior that could enable future lifesaving therapies. Stem cells are like the emergency tool kit of the human body. They have the unique...
A vision of the future: Stem cells offer hope for retinal degeneration
By Hannah Thomasy, PhD - Exploring Drug Discovery and Development News - The black rat rested calmly in a clear tube, its nose twitching gently as it sniffed the air. Its eyes followed the parade of vertical black and white bars scrolling from left to right across a...
What New Gene Therapy Means For Sickle Cell Patients
Dr. Omer Awan MD MPH CIIP - Forbes - Recently, a 12-year-old boy became the first patient with sickle cell disease to begin commercially approved gene therapy that could potentially cure the condition. Read the article - Click Here
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