News and Opinions
Organ-Chips May Help Unlock the Mystery of ALS
By Christina Elston - Cedars Sinai - Cedars-Sinai’s Lifelike Laboratory Model Is a New Way for Investigators to Study Motor Neurons That Die in Patients With the Neurodegenerative Illness Using stem cells from patients with ALS (amyotrophic lateral sclerosis),...
Japan is helping lead the way in regenerative medicine
By Alex (Guangyao) Xu - The Japan Times - In a quiet operating room on Kyoto University’s medical campus, a team of researchers slipped a syringe of lab-grown neurons into the brain of a living person. Leading the trial was Jun Takahashi, a neurosurgeon with the kind...
FDA blocks new clinical trials that ship cells from US to China
By Nick Paul Taylor - Fierce Biotech - The FDA has stopped new clinical trials that export American citizens’ living cells from the U.S. to “China and other hostile countries for genetic engineering and subsequent infusion” back into American patients. Officials said...
Francis Collins Reflects on Human Genome Project’s 25th Anniversary
By Alex Philippidis , Fay Lin, PhD and Kevin Davies, PhD - Genetics and Biotechnology News - The reference genome was a “bridge into the future,” but there is still much work that needs significant support. 25 years ago, Francis Collins, MD, PhD, led the international...
FDA Greenlights Twice-A-Year HIV Prevention Drug
By Antonio Pequeño IV - Forbes - Yeztugo, a twice-a-year antiviral shot to prevent HIV, was approved by the Food and Drug Administration on Wednesday, marking a major advance in battling AIDS. Key Facts The drug (which has the generic name lenacapavir) will become...
New Immunotherapy Reverses Cholesterol Damage in Heart Cells
By Sant Pau Research Institute - SciTechDaily - A new antibody treatment prevents cholesterol buildup in heart mitochondria and restores energy production, offering hope for future heart disease therapies. An international team of researchers has uncovered how...
Designing blood vessels for 3D printed hearts
By Stanford Report - Stanford researchers have developed a faster, more precise way to model and print vascular systems, solving a critical challenge in fabricating transplantable organs from patients’ own cells. There are more than 100,000 people on organ transplant...
People With Severe Diabetes Are Cured in Small Trial of New Drug
By Gina Kolata - New York Times - Most in a small group of patients receiving a stem cell-based infusion no longer needed insulin, but the drug may not suit those with more manageable type 1 diabetes. A single infusion of a stem cell-based treatment may have cured 10...
Germany calls for medicine to treat aging, not just disease
By Eleanor Garth - Longevity.Technology - Leopoldina issues policy paper urging integration of geroscience into national healthcare and research infrastructure. Germany’s National Academy of Sciences Leopoldina has published a detailed policy paper calling for a...
Dozens of states sue to block the sale of 23andMe personal genetic data
By The Associated Press - PORTLAND, Ore. — Twenty-seven states and the District of Columbia on Monday filed a lawsuit in bankruptcy court seeking to block the sale of personal genetic data by 23andMe without customer consent. The lawsuit comes as a biotechnology...
Blocking a single enzyme rewires limb regrowth in axolotls
By Vijay Kumar Malesu - Medical life Sciences News - In a recent study published in the journal Nature Communications, researchers in the United States explored how cytochrome P450 family 26 subfamily B member 1 (CYP26B1)-mediated retinoic acid (RA) breakdown...
Son’s diabetes diagnosis sent scientist on quest for cure
by Kermit Pattison - The Harvard Gazette - Decades later, Doug Melton and team are testing treatment that could make insulin shots obsolete. Doug Melton’s life irrevocably changed the day his child was diagnosed with a life-threatening disease. But unlike most other...
Research Spotlight: Preventing stalling to improve CAR-T cells’ efficacy against tumors
By Mass General Brigham - Marcela Maus, MD, PhD, director of the Cellular Immunotherapy Program and the Paula J. O'Keeffe Endowed Chair of the Mass General Cancer Center, is senior author and Stefanie Bailey, PhD, Hana Takei, and Giulia Escobar, PhD of the Krantz...
Stem cell platform aims to recreate brain’s immune system using lab-grown human microglia cells
by Harvard University - Microglia are a specialized type of immune cell that accounts for about 10% of all cells within the brain and spinal cord. They function by eliminating infectious microbes, dead cells, and aggregated proteins, as well as soluble antigens that...
After groundbreaking CRISPR therapy, a homecoming
By Meghana Keshavan - Stat News - From my colleague Jason Mast: KJ Muldoon, the first infant treated with a personalized gene-editing drug, has been discharged from the hospital for the first time in his life, the Children’s Hospital of Philadelphia announced Tuesday....
How our bones are repaired by skeletal stem cells: Scientist discover four major subtypes
by Sarah Williams, Stanford University - MedicalXpress - Whether you are a competitive athlete or an older adult, strong bones are essential—not only for movement, but also for overall health. Now, a new study has shed new light on how our bones are maintained and...
No More Transplants? New Gene Therapy Targets Blood Stem Cells Directly
By Fondazione Telethon - SciTechDaily - Researchers have identified an early postnatal window that allows gene transfer to circulating blood stem cells, advancing the development of potential treatments for genetic disorders. A team of scientists from the San...
Stem cell therapies advance in Parkinson’s disease and beyond
By Natalie Healey - Nature Medicine - Landmark trials using stem cells to treat Parkinson’s disease in the USA and Japan mark a turning point for cell therapy in neurodegeneration. Similar approaches to Alzheimer’s disease and amyotrophic lateral sclerosis are also...
The Potential Impact Of U.S. Tariffs On The Biotech Sector: Manufacturing, Funding, And Clinical Trials
By Raymond Forslund, PhD - Clinical Leader - The imposition of tariffs by the United States government has introduced significant uncertainties across various industries, including biotechnology. This white paper examines the potential ramifications of these tariffs...
Florida lawmakers approve bill to improve access to some unapproved stem cell therapies
By Rick Mayer - WUSF-NPR - Health News Florida The measure authorizes physicians to perform the treatments for orthopedics, wound care or pain management with strict requirements to ensure safety and ethics. Before the annual session ended last week, the Florida...
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