News and Opinions

To Ward Off Aging, Stem Cells Must Take Out the Trash

Mar 30, 2023 | News & Opinions

Nicole Mlynaryk – University of California Sab Diego News

UC San Diego scientists find stem cells’ unique way of discarding misfolded proteins could be the key to maintaining long-term health and preventing disease

In humanity’s ongoing quest for the elixir of life, the science keeps pointing to stem cells. Research increasingly shows that maintaining stem cell fitness promotes a long healthspan, and new findings show keeping stem cells clean and tidy is an integral step.

In a study published March 21, 2023 in Cell Stem Cell, researchers at University of California San Diego School of Medicine found that blood stem cells use an unexpected method to get rid of their misfolded proteins, and that this pathway’s activity degrades with age. The authors say boosting this specialized garbage disposal system could help protect against age-related diseases.

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