News and Opinions
Nanofiber-Hydrogel Loaded with Stem Cells Shows Success Treating Severe Complication of Crohn’s Disease
by Johns Hopkins University Johns Hopkins researchers develop injectable hydrogel composite that promotes regenerative healing in an animal model of Crohn’s perianal fistulas In a new study using a rat model of Crohn’s disease, a biodegradable hydrogel composite...
California agency invests $4 million in stem cell treatment for Parkinson’s Disease
By Esteban Cortez - The Stem Cellar The California Institute for Regenerative Medicine (CIRM) is investing $4 million in a late-stage preclinical project by Ryne Bio aiming to improve treatment for Idiopathic Parkinson’s disease (PD). PD is characterized by a loss of...
Options for laryngeal regeneration
By Susan Buckles - Mayo Clinic Mayo Clinic is using 3D printing as a new option to heal the larynx after cancer or traumatic injury. David Lott, M.D., a Mayo Clinic otolaryngologist and head and neck surgeon, is an expert who can speak about a pioneering procedure...
CRISPR gene-editing may boost cancer immunotherapy, new study finds
By Rob Stein - NPR News Katie Pope Kopp went through round after round of chemotherapy and a stem cell transplant to treat her non-Hodgkin lymphoma. But nothing could beat it. "I went back to get a PET scan in May of 2020, and that's when they found that my...
Stem Cell–Based, Cryopreservable Bioimplants for Arthritis
By Anjali A. Sarkar, PhD - Genetic Engineering & Biotechnology news Researchers are developing off-the-shelf treatments to save joints before they wear out Osteoarthritis is a progressive disease where the protective layer of articular cartilage that cushions the...
What patients do and don’t know about stem cell therapy
by Lynda Charters - Ophthalmology Times A recent survey of retinal clinic patients reveals a lack of awareness of the risks and safety issues associated with stem cell therapies. Intravitreal injections of unapproved stem cell therapies have resulted in irreversible...
The future of replacement organs is (quite possibly) here: Robust human intestinal organoids created in a lab
by Tokyo Medical and Dental University - Phys.Org Growing miniature organ-like tissues in the lab is already within our reach. Now, researchers from Japan have developed a new approach that enables intestinal mini-organs to be grown more easily and efficiently in the...
Genetic cause of ALS and dementia repaired by RNA-targeting strategy developed at UF Scripps
By: Stacey DeLoye UFHealth News Scientists at UF Scripps Biomedical Research have developed a potential medicine for a leading cause of ALS and dementia that works by eliminating disease-causing segments of RNA. The compound restored the health of neurons in the lab...
Highly Mature Neurons Created
By Technology Netowrks Northwestern University-led researchers have created the first highly mature neurons from human induced pluripotent stem cells (iPSCs), a feat that opens new opportunities for medical research and potential transplantation therapies for...
JPM23’s Medtech Tidbits: Reporting from San Francisco
By Andrea Park, Conor Hale - Fierce Biotech SAN FRANCISCO—After years of stops, starts and stops again, the J.P. Morgan Healthcare Conference has returned to the city by the bay in full form. Below we've compiled the biggest medtech news so far, bite-sized—from both...
Scientists Identify How a Biological Pathway Leads Stem Cells to Die or Regenerate
Manipulating Cell Signaling Can Possibly Ensure the Body Has a Healthy Amount of Cells By Stephanie Cajigal - Cedars Sinai A new study led by Cedars-Sinai and the University of California, San Francisco (UCSF), has determined that altering a cellular process can lead...
Genetics, Alzheimer’s And AI — Why 2023 Could Be The Year For Biotech Stocks
By Allison Gatlin - Investors.com If there's one overarching theme that investors in biotech stocks should pay attention to in 2023, it's "genetic medicine, genetic medicine, genetic medicine," says Christopher Anzalone. Anzalone is biased, of course. He's the chief...
O.K. Corral: FDA sets stage to appeal California Stem Cell Treatment Center decision
Michael Druckman, Meredith Manning, and Ashley Grey - Hogan Lovells Last year, a federal court in California ruled against the U.S. Food and Drug Administration (FDA) in a matter where the government alleged that a stem cell clinic’s products should be regulated as...
Teaming Up Two Biotech Winners to Fight Cancer: CRISPR and CAR T
by William A. Haseltine - Forbes Here we describe early clinical trial results on combination CRISPR and CAR T therapy, a sequel to an earlier, introductory piece. Other alternative CAR T designs include mRNA vectors to create temporary CAR T cells and the use of...
The future of replacement organs is (quite possibly) here: Robust human intestinal organoids created in a lab
by Tokyo Medical and Dental University - Phys.org Growing miniature organ-like tissues in the lab is already within our reach. Now, researchers from Japan have developed a new approach that enables intestinal mini-organs to be grown more easily and efficiently in the...
MS patients could be offered stem cell transplants as a first-line treatment in new world-first trial
A world-first trial is investigating if stem cell transplantation could be used in patients with aggressive multiple sclerosis (MS) as a first-line treatment. By University of Sheffield The study launched by the University of Sheffield and Sheffield Teaching Hospitals...
Scientists Receive $4.8M to Pursue Gene Therapy for ‘Incurable’ Disease
CIRM grant will fund novel gene therapy aiming for one-time, lifelong treatment of Friedreich’s ataxia, a progressive neuromuscular disorder; second CIRM grant will advance efforts to leverage UC San Diego research on another rare disease By Scott LaFee - UC San Diego...
Scientists identify neurons that restore walking after paralysis
By EPFL News A new study by scientists at the .NeuroRestore research center has identified the type of neuron that is activated and remodeled by spinal cord stimulation, allowing patients to stand up, walk and rebuild their muscles – thus improving their quality of...
A different kind of cell signal: New method enables clear, precise imaging of human cells
Researchers at the Beckman Institute for Advanced Science and Technology developed a new method to ‘see’ the fine structure and chemical composition of a human cell with unmatched clarity and precision. By Jenna Kurtzweil - University of Illinois Beckman Institute...
FDA no longer needs to require animal tests before human drug trials
By Meredith Wadman - Science New law welcomed by animal welfare groups, but others say change won’t happen fast New medicines need not be tested in animals to receive U.S. Food and Drug Administration (FDA) approval, according to legislation signed by President Joe...
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