News and Opinions

by Press Office - King’s College London - neurosciencenews.com Summary: Results of a phase three clinical trial of a novel brain cancer vaccine, DCVax-L, that uses a patient’s stem cells to target cancer cells extended survival by many months to years for glioblastoma...

By Elaine Fuchs - The Rockefeller University Image Caption: TGF beta signaling (red) is one way that the environment causes cancer stem cells at the stroma-tumor border (green) to become invasive. Living cells are dyed blue. Credit: Shaopeng Yuan What drives tumor...

By Hayden E. Klein and Skylar Jeremias - AJMC Jana K. Dickter, MD, associate clinical professor, Division of Infectious Diseases, City of Hope, discusses a patient's experience being the oldest person to successfully undergo a stem cell transplant while living with...

Reference genomes used to direct the gene editor fail to account for human diversity By Jocelyn Kaiser - Science The 10-year-old gene-editing tool known as CRISPR is indispensable for engineering plants, tailoring lab animals, and probing basic biology. But there’s a...

Toddler Thrives with Same Disease That Ended Siblings’ Lives By University of California San Francisco When Zahid and Sobia Bashir discovered their fetus had the same genetic disease that took the lives of two of their young children, they didn’t hesitate to sign up...

Addresses major gap in effectiveness of immunotherapy Mount Sinai Press Release New York, NY - Mount Sinai and Memorial Sloan Kettering Cancer Center (MSK) researchers have identified therapies that can help patients with the blood cancer multiple myeloma who try an...

By University of California - The Guardian UC San Diego School of Medicine’s Translational Neuroscience Institute made its latest breakthrough in the treatment of spinal cord injuries after the culmination of 30 years of research. In a paper published on Aug. 22, a...

By Joe Dangor - Mayo Clinic ROCHESTER, Minn. — Researchers at Mayo Clinic Comprehensive Cancer Center have identified a gene marker that may lead to a more effective, precision treatment for pancreatic ductal adenocarcinoma (PDAC). The researcher’s findings are...

By Heidi Ledford - Nature ‘Most complicated therapy ever’ tailors bespoke, genome-edited immune cells to attack tumours. A small clinical trial has shown that researchers can use CRISPR gene editing to alter immune cells so that they will recognize mutated proteins...

By Noah Fromson - University of Michigan Health Image caption: Human neural stem cell transplants (green) survive and migrate throughout the mouse brain (blue) when given a novel monoclonal antibody treatment. Michigan Medicine Using antibodies instead of traditional...

By Susan Murphy - Mayo Clinic Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) — a type of immunotherapy that reprograms a patient's T cells to recognize and destroy cancer cells — has revolutionized the treatment of blood cancers. While the technique has...

By Anna MacDonald and Sarah Whelan - Technology Networks Cell and gene therapy is a field of personalized medicine, driving the innovation of medicine and revolutionizing the way we treat disease. Gene therapies use DNA or other genetic material to edit a patient's...

by Margarida Maia, PhD - Parkinson's News Today A request to launch a first Phase 1/2 clinical trial of a stem cell-based therapy in people with Parkinson’s disease has been approved by the Swedish Medical Products Agency. The therapy, called STEM-PD, consists of stem...

by Nature Italy By studying how hematopoietic stem cells respond to age and damage, Raffaella di Micco aims to anticipate the long-term effects of some gene therapies. This is a scene from my daily routine in my lab in Milan where we study hematopoietic stem cells,...

By The Ottawa Hospital - The Globe and Mail Treatment developed at The Ottawa Hospital can halt MS progression and potentially reverse symptoms When Geneviève Bétournay developed blurry vision and pain in her hips 12 years ago, she was shocked to be diagnosed with...

By Medical News Life Sciences Researchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have used CRISPR/Cas9 technology to engineer donor T cells to try to treat seriously ill children with...

By Genetic Engineering & Biotechnology News A study by scientists at the Icahn School of Medicine at Mount Sinai, the James J. Peters Veterans Affairs Medical Center, the Yale School of Medicine, and the New York Stem Cell Foundation Research Institute (NYSCF) has...

By Frances Stead Sellers - The Washington Post For the burgeoning population of covid long-haulers, there is an abundance of new treatment options: Specially formulated nutraceuticals imported from India that promise to “get you life back from covid.” Pure oxygen...

by By Beth JoJack - Medical News Today For the first time, researchers have used CRISPR gene-editing technology to substitute a gene in a patient’s immune cells to redirect those cells to fight cancer. Details of a small human clinical trial using this approach are...

By Lei Lei Wu - EndpointsNews MIT scientists have developed a tool that they say can insert large gene sequences where they want in the genome. In a paper published Thursday in Nature Biotechnology, MIT fellows Omar Abudayyeh, Jonathan Gootenberg and colleagues detail...